Septic shock

Severe infections, especially Gram-negative bacterial infections, can often cause septic shock. Septic shock, also known as septic shock, refers to sepsis syndrome with shock caused by microorganisms and their toxins and other products. Microorganisms, toxins, and cell wall products in infected foci invade the blood circulation and activate various host cells and humoral systems; produce cytokines and endogenous mediators, affect various organs and systems of the body, affect their perfusion, and cause tissue Cell ischemia and hypoxia, metabolic disorders, dysfunction, and even multiple organ failure. This critical syndrome is septic shock. Therefore, septic shock is the result of the interaction between microbial factors and the body's defense mechanism. The virulence of microorganisms and the internal environment and response of the body are important factors determining the development of septic shock.