Perimenopausal syndrome

Perimenopausal syndrome, also known as menopausal syndrome (MPS), refers to a series of symptom groups that are mainly caused by autonomic nervous system dysfunction caused by fluctuations or reductions in sex hormones before and after menopause. Menopause can be divided into natural menopause and artificial menopause. Natural menopause refers to the exhaustion of follicles in the ovary, or the remaining follicles have lost their response to gonadotropins, the follicles no longer develop and secrete estrogen, and cannot stimulate the growth of the endometrium, leading to menopause. Artificial menopause refers to the surgical removal of bilateral ovaries or other methods to stop ovarian function, such as radiation therapy and chemotherapy. Excision of the uterus alone while retaining one or both ovaries is not considered artificial menopause. Judgment of menopause is mainly based on clinical manifestations and hormone determination. Essence is more likely to occur in artificial menopause. The age of menopause is related to the number of follicle reserves, follicle consumption, nutrition, region, environment, smoking and other factors, but not to education, body size, age at menarche, number of pregnancy, age of last pregnancy, long-term use of contraceptives and other factors. Inhibiting ovulation with contraceptives does not delay menopause, because the consumption of eggs does not mainly depend on ovulation, and a large number of follicles disappear through atresia.