Meningococcal meningitis

Meningococcal meningitis is a purulent meningitis caused by meningococcal (Neisseria meningitis, Nm). Pathogens invade the blood circulation from the nasopharynx, and are finally confined to the meninges and spinal membranes, forming purulent cerebrospinal membrane lesions. The main clinical manifestations are meningeal irritation such as protruding fever, headache, vomiting, ecchymosis of the skin, petechiae and neck stiffness. Cerebrospinal fluid showed purulent changes. In addition, meningococci do not invade the meninges and only manifest as sepsis, in which severe cases can occur as a flare-up. Infection can also occur in the upper and lower respiratory tracts, joints, pericardium and eyes. The disease is found all over the world, and it is sporadic or pandemic, with high incidence in children.