Fool-like eyelid fissure distortion
Introduction
Introduction Stupid-shaped splitting and twisting means that the gap between the edges of the upper and lower eyelids is distorted. It is related to hereditary factors, usually caused by the short arm of chromosome 5. The clinical manifestations are weeks to months after birth, and there are kittens crying, severe mental retardation, large interocular distance, epicanthalfolds, short head deformities, and congenital cleft palate. Distorted, small jaw muscle tension and strabismus, the face is very round like a full moon, looks more fat and commonly known as the full moon face.
Cause
Cause
The short arm of chromosome 5 is missing.
Examine
an examination
Related inspection
Eyelid examination chromosome
A few weeks to months after the birth, the kittens are crying, severe mental retardation, and the distance between the eyes is too long. The epicanthalfolds, the short head deformity, the full moon face, and the anti-congenital pattern are cracked and distorted. Small jaw muscle tension and strabismus.
Physical examination and chromosome examination can be diagnosed.
Diagnosis
Differential diagnosis
Cleft palate: Congenital cleft palate syndrome is characterized by less cleft palate. It is autosomal dominant. It may be that the embryo is 3 months before and after, due to the increase in the number of inhibitory development of maxillary processes, and the imbalance between the developmental factors of the outer nasal processes. Therefore, there is also an increase in the distance between the two eyes, and the outer point of the lower tear point. More common among Japanese.
The sacral margin is sagged in the transverse "S" shape: due to the acute sacral lacrimal gland disease, it is characterized by a horizontal "S" shape sag, which is a clinical manifestation of acute sacral lacrimal gland inflammation. Acute axillary lacrimal gland: redness, swelling, pain, tearing discomfort on the lateral side of the upper eyelid, sag in the transverse "S" shape, swelling can spread to the sputum, cheeks, swollen lymph nodes in the ear, tenderness, sputum And solid mass, there is tenderness, no adhesion to the sacral wall and sacral margin, conjunctival congestion and edema on the sacral conjunctiva, lacrimal gland tissue congestion, mucus-like secretions, may be associated with fever, headache, general malaise, if Early appropriate anti-infective treatment, more than 1 to 2 weeks of inflammation subsided, and some sub-acute, only 1 to 2 months to resolve, a small amount of suppuration from the upper conjunctiva perforation, pus discharge into the conjunctival sac or temporarily formed fistula, It can heal in 2 to 3 weeks.
Eyelid malformation: caused by trauma, infection, tumor resection and other reasons, scar contracture can cause abnormalities in the shape of the eyelids, eyelid valgus and insufficiency. Eyelid valgus deformity is a common problem in patients with facial burns. Because the eyelids can not be closed, the eyeballs are often exposed and stimulated, causing the eyeballs to become red, painful, have a foreign body sensation, and often shed tears. If the cornea is exposed for a little longer, the eye fluid is not wet, and exposed keratitis and corneal ulcers can occur. If the treatment is not timely, it can cause blindness.
A few weeks to months after the birth, the kittens are crying, severe mental retardation, and the distance between the eyes is too long. The epicanthalfolds, the short head deformity, the full moon face, and the anti-congenital pattern are cracked and distorted. Small jaw muscle tension and strabismus.
Physical examination and chromosome examination can be diagnosed.
