osteolytic lesions
Introduction
Introduction Osteolytic lesions are more common in the proximal ends of the skull, pelvis, spine, ribs, femoral long bones, and tibia. Often in a variety of sizes, the shape of the circle or ovate is high and the shape is clear, the edge is clear, and there is no new bone formation around. Osteolytic destruction is caused by multiple myeloma and Langerhans cell histiocytosis. The disease is complicated by multiple myeloma, multiple myeloma nephropathy and multiple myeloma in the elderly. There is currently no effective treatment for this disease. Improving living habits and actively treating diseases such as myeloma are effective measures to prevent the disease.
Cause
Cause
Caused by multiple myeloma, it is one of the typical positive signs of multiple myeloma. In addition, Langerhans cell histiocytosis can also cause osteolytic destruction.
Examine
an examination
Related inspection
X-ray lipiodol angiography (MRI)
1, the age of good hair is more than 40 years old, more men than women.
2, there may be no obvious symptoms in the early stage of the disease, only the symptoms of increased ESR, anemia, proteinuria and so on.
3, may have bone and joint, low back pain, skull, thoracic rib tumor formation, with chest ribs, clavicular junctions with bead-like nodules and osteolytic drilling or rat bite-shaped round bone defects, can be Pathological fractures, paraplegia, intercostal and sciatica.
4, can damage the kidney and cause proteinuria, renal tubular disease, nephrotic syndrome, uremia and so on.
5, due to increased blood viscosity caused by dizziness, headache, visual impairment, chest tightness, dizziness, bleeding and other symptoms.
6, easy to cause lung and urinary tract infections.
Diagnosis
Differential diagnosis
Clinically often differentiated from osteosarcoma.
Osteosarcoma often uses pain as an early symptom, which can occur before the onset of the tumor, initially as intermittent pain, and gradually becomes persistent severe pain, especially at night. Malignant tumor pain occurs earlier and more severely, often with a history of local trauma. The tumor at the proximal end of the bone is large, the hardness is different, there is tenderness, the local temperature is high, the vein is dilated, and sometimes the pulsation can be felt, and there may be a pathological fracture. Whole body health gradually declines to failure, and most patients have lung metastases within a year.
