hypertrophic scar
Introduction
Introduction Hyperplastic scar (hyperplastic scar), also known as hypertrophic scar or hypertrophic scar, is not qualitatively different from keloid in histopathology. After the skin damage is healed, the scar continues to proliferate and develop into a hypertrophic scar. Hypertrophic scars protrude from the skin, irregular in shape, uneven, flushed and bloody, and firm in texture. It has a burning and itching sensation, which is exacerbated by increased ambient temperature, emotional agitation, or eating spicy and irritating food.
Cause
Cause
1, local factors, including foreign bodies, inflammation, traction and so on. Foreign objects, such as dust, talcum powder, cotton fibers, knots and certain chemicals falling into the wound. In addition, there are keratin precipitated after cell destruction. Inflammation, such as long-term naked infection before wound healing, excessive growth of granulation tissue, recurrent infection caused by residual hair follicles or glandular tissue wrapped in scar after deep burn wound healing. Pulling, such as consistent with the skin's natural texture, wrinkles, or scars at the joints, is constantly being pulled, or even broken, and then repeatedly ruptured and healed. Stimulation of these local factors can lead to the proliferation of scars.
2, systemic factors, such as young adults, women, especially pregnant women and hyperthyroidism patients are prone to hypertrophic scars, and rarely seen in the elderly, which may be related to the secretion of estrogen and sputum secretion. In addition, factors such as race, heredity, and physical quality are also related to scar hyperplasia, but the exact mechanism remains to be elucidated.
Examine
an examination
1. Skin Test - Skin tests are the most commonly used specific tests, including patches, scratches, spurs, and intradermal injections. Clinically, it is most commonly used for picking and intradermal tests. If the test is negative, it can be used for intradermal test.
METHODS AND PRINCIPLES: Specific patients with specific allergens can induce specific IgE, which adheres to the IgE receptor on the surface of mast cells in the skin or submucosa, when it meets with allergens entering the body again. The bridging of one allergen with two IgE antibodies causes a series of biochemical processes in the mast cells, releasing allergic mediators, producing wheal, blushing or itching in the skin. On the inside of the patient's forearm, routine disinfection, and then use OT syringe, No. 4 injection needle to inhale different kinds of allergen infusion solution into the forearm medial skin 0.02ml, the distance between antigen points is 2.5cm. After 15 to 20 minutes of skin test, skin reactions, local wheal and blush size were observed and compared with control points.
2, Niacin (Niacin) - Niacin is also known as vitamin B3, or vitamin PP, molecular formula: C6H5NO2, heat, can sublimate. It is one of the 13 kinds of vitamins necessary for the human body. It is a water-soluble vitamin and belongs to the vitamin B family.
Niacin is mainly present in foods in the form of coenzymes and is absorbed in the stomach and small intestine after digestion. After absorption, it enters the liver through the portal vein in the form of niacin. Excess niacin is mostly excreted from the urine via methylation.
Niacin is converted into nicotinamide in human body. Niacinamide is a component of coenzyme I and coenzyme II, which participates in lipid metabolism in the body, oxidation process of tissue respiration and anaerobic decomposition of carbohydrates.
Niacin is one of the vitamin B complexes and acts as an anti-pricken skin factor. Also known as Niacin (niacin) in the United States. The lack of symptoms is () pellagra, which has three symptoms: dermatitis, diarrhea, and dementia. Black tongue disease can occur in dogs.
Diagnosis
Differential diagnosis
Differential diagnosis of hypertrophic scars:
1. Contracture scar: A contracture scar is a scar named after the dysfunction caused by it. More common after deep burn healing, due to scar contraction, often lead to shape changes and dysfunction, long-term scar contracture can affect the development of bones, muscles, blood vessels, nerves and other tissues, should be treated early.
2, scorpion scar: scar to scorpion, shaped like duck plague. Such scars occur in the flexion of the joint, and can also be seen in the opening of the lumen of the organ, such as the mouth, nostrils, urethra, vaginal opening. A scar-like scar is actually a characteristic manifestation of scar contracture in the above-mentioned special parts.
3, depressed scars: skin dermis and subcutaneous tissue defects can cause depressed scars, often caused by hemorrhoids, trauma, chickenpox.
