Indentation of the skin
Introduction
Introduction It is an allergic reaction to skin blood vessels, and the formation of allergic reactions is caused by internal and external factors. There is a special protein in the serum of such patients, which is immunoglobulin IgE. When such proteins are combined with allergens, the body will cause a series of reactions, and finally the mast cells around the blood vessels of the skin will release a large amount of histamine. Histamine can cause skin vasodilation, and the serum will ooze out of the blood vessels, causing itching. At this time, the skin scratch test is positive.
Cause
Cause
Mostly, the skin undergoes allergic reaction after being physically stimulated by the outside, so that the mast cells release the bioactive substances of histamine, causing the skin to expand and expand the permeability, so that the plasma and tissue fluid penetrate into the dermis.
Examine
an examination
Related inspection
Rapid plasmin cyclic card experiment rapid plasma responsiveness test radioimmunoassay adsorption test (RAST)
(1) The skin of the patient is very sensitive to external mechanical stimuli. There is usually no wheal on the skin. If the skin is scratched with nails or blunt instruments, strip-like bulging scratches appear quickly in the affected area.
(2) It can be used at any age without obvious cause of illness. Infectious lesions, diabetes, thyroid dysfunction, and menopause are often associated with the disease. Trauma, clothing, friction, bandages, scratching, etc. can cause wind whistles and itching.
(3) The course of the disease is uncertain and can last for several months or for a long time.
(4) In addition, in rare cases, after the skin scars subsided for half an hour to 5 or 6 hours, the wheal reaction appeared in the original part and lasted for 48 hours, which is called delayed skin scratching.
Diagnosis
Differential diagnosis
Squeeze syndrome is a part of the limbs or trunk muscles that are subjected to heavy objects for a long time and appear after the squeezing is released. Clinically, acute renal failure characterized by limb swelling, myoglobinuria, and hyperkalemia.
