decreased stomach acid

Introduction

Introduction Reduced gastric acid secretion: related to the extent and extent of damage to the gastric mucosa. Can be seen in gastritis, gastric ulcer, stomach cancer. It can also be seen in pernicious anemia. The gastric acid secretion of patients with adult pernicious anemia is decreased. The pH value of gastric juice before and after stimulation may be above 6. Localized or diffuse hyperemia of the gastric mucosa, edema, surface epithelial cell necrosis and detachment can produce superficial erosion, due to submucosal vascular damage, causing hemorrhage or plasma extravasation, deep erosion can involve the corpus, generally does not exceed the mucosal muscle layer .

Cause

Cause

Gastritis refers to inflammation of the gastric mucosa caused by various causes, and is a common digestive tract disease, which is classified into acute and chronic. The most common cause is caused by bacteria and toxins after food contamination.

Common causes are chemical stimuli, such as heavy drinking and overdose of salicylates.

Bacterial infections and toxins such as staphylococcal food poisoning, scarlet fever, pneumonia.

Viral infections such as viral gastroenteritis, measles, hepatitis, flu, etc.

Allergies, such as allergies to aquatic shellfish.

Examine

an examination

Related inspection

Basal gastric secretion

The clinical manifestations of gastritis are different in severity. There are often loss of appetite, nausea, vomiting, upper abdominal pain or colic, diarrhea, chills, headache and tendon. Bacterial simple gastritis has a short incubation period, such as staphylococcal infection, 1-6h after eating, 4-24h of Salmonella, and 9-12h of halophilic bacteria. At the same time with enteritis diarrhea, it is also known as acute gastroenteritis. Generally, it will improve after 1-2d. In severe cases, symptoms such as fever, water loss, acidosis and shock may be seen.

Diagnosis

Differential diagnosis

Lack of stomach acid, bacteria can easily multiply in the stomach, can cause chronic gastritis. Chronic gastritis refers to various chronic gastric mucosal inflammatory lesions caused by different causes. It is a common disease and one of the most common diseases of the army. Its incidence rate ranks first among various stomach diseases. Since the wide application of fiber endoscopy, the understanding of this disease has been significantly improved. Chronic gastritis often has a certain degree of atrophy (mucosal loss of function) and metaplasia, often involving the cardia, accompanied by loss of G cells and decreased secretion of gastrin, may also involve the body of the body, accompanied by loss of acid secretion glands, leading to stomach acid, Reduction of pepsin and endogenous factors. Chronic gastritis is non-specific and has few signs. X-ray examination generally only helps to rule out other stomach diseases, so it is necessary to rely on gastroscopy and gastric mucosal biopsy. Helicobacter pylori can be found in the gastric mucosa in about 50-80% of patients in China.

Excessive stomach acid: it will hurt the stomach, duodenum, and even burn the mucous membranes and muscles, causing diseases such as stomach ulcers or duodenal ulcers. When you eat more acidic foods, such as plums, vinegar, etc., it will stimulate the secretion of gastric acid. At this time, the stomach acid will penetrate into the damaged gastric mucosa (ulcer), which will stimulate the gastrointestinal tract and cause pain.

Hypergastrinemia, which is divided into two types: high gastric acid hypergastrinemia and low gastric acidity or no acid hypergastrinemia. In patients with gastrinoma, serum gastrin levels are high, and more often accompanied by gastric mucosal hyperplasia, hypertrophy. The abnormal increase of fasting gastrin concentration in patients with ulcer disease and the stimulation of gastrin response in meals are abnormal. Excessive gastrin activity is an important mechanism for the development of peptic ulcer in children. Fasting gastrinemia is one of the characteristics of pediatric duodenal ulcer different from adult.

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