Buried tooth
Introduction
Introduction The clinical manifestations of Gardner syndrome can be seen in abnormal tooth development such as multiple teeth, dental tumors, and buried teeth. Gardner syndrome, also known as Weiner-Gardner syndrome, familial multiple colon polyp-osteoma-soft tissue tumor syndrome, familial colon polyposis is a chromosomal dominant genetic disease, which is a multifaceted manifestation of a single gene. In 1905, Gardner reported that colonic polyposis and familial osteoma soft tissue tumors and colon cancer were more likely. Later, in 1958, Smith proposed that the triad of colon polyps, soft tissue tumors and osteoma is the intrinsic pathogenesis of Gardner syndrome. Colon polyps are adenomatous polyps, and the cancer rate is 50%. The bone tumors are benign. Both men and women can suffer and have a family history.
Cause
Cause
The cause is unknown, and genetic factors are found. Some people think that it may be related to the lack of delayed immune response in the small intestine. Pathologically, the gastrointestinal tract has obvious mucosal inflammatory reaction, which is most obvious in the stomach and small intestine. Polyps are most common in the duodenum. The end of the ileum is also more, and the diameter of the polyps can vary from a few millimeters to 3 centimeters. Most scholars believe that polyps are young-type hamartoma-like polyps, and gastric mucosal lesions are similar to Menetriey.
Examine
an examination
Related inspection
Oral X-ray examination of oral endoscopic pulp vitality
Endoscopy and X-ray examination can identify digestive polyps and osteoma. It can be diagnosed by colon polyps, soft tissue tumors and osteoarthritis.
1. Multiple polyps in the colon; the main symptoms are diarrhea, mucus or bloody stools, and the polyps of other parts of the digestive tract such as the stomach and duodenum are higher.
2. Soft tissue tumors: occur in the face, trunk or limbs, mostly sebaceous cysts, fibroid epidermis cysts, lipomas.
3. Osteosarcoma: occurs in the flat bones such as the jaw, humerus, and sphenoid bone. It is still visible in abnormal tooth development, such as multi-tooth, dental tumor, and buried teeth.
Diagnosis
Differential diagnosis
The disease should be associated with hereditary gastrointestinal polyposis with mucocutaneous pigmentation (Peutz-Jegher syndrome), hereditary colon polyp syndrome (Canada syndrome), Turcot syndrome, Gardner syndrome and other gastrointestinal polyposis Identification, these diseases are not accompanied by abnormal changes in ectoderm, which is helpful for identification.
