oropharyngeal vesicular lesions
Introduction
Introduction The oropharyngeal vesicular lesion is a clinical symptom caused by the infection of the herpes simplex virus. B virus disease (B virus disease) is also known as herpes virus simiae, which is named after the infection of monkeys. Skin damage, lymphadenitis and flu-like syndrome can occur in people who are infected with BV monkeys or scratches, and even toxic encephalitis.
Cause
Cause
(1) Causes of the disease
The BV particles are about 160-180 nm in diameter and consist of an envelope and a nucleocapsid, which are internally linear ds-DNA. Its morphological characteristics and viral structure are similar to HSV, and there is more homology between viral antigens.
(two) pathogenesis
Human infection with BV is primarily through direct contact with infectious saliva or tissue cultures of monkeys. If the infected monkey bites or scratches and directly touches the monkey's tissue or body fluid, the damaged skin of the human body is contaminated with the saliva of the monkey, or laboratory operation pollution.
Examine
an examination
Related inspection
Oral endoscopic oral X-ray examination
The pathogenic effect of BV on humans is much stronger than that on monkeys. The incubation period after virus infection is 2 days to 10 years, and once the disease occurs, the situation is serious. Local skin appears erythema, induration, blister formation after 1 to 3 days; systemic symptoms, including fever, flu-like syndrome, especially headache, myalgia, fatigue, etc., lymphadenitis, lymphangitis, oropharynx Blisters and the like. BV infectious encephalitis can occur even if the condition continues to worsen, and even life-threatening.
Recently exposed to infected monkeys, typical lesions in the infected area, with the symptoms of systemic "flu-like syndrome", that is, the possibility of considering the disease; if BV is isolated from the patient's blister fluid, tissue homogenate, or detected from the patient's serum A specific antibody can be used to make a diagnosis.
The isolation of BV from patient blister fluid, tissue homogenate, or the detection of specific antibodies from patient sera is helpful in diagnosis.
Diagnosis
Differential diagnosis
Differential diagnosis of oropharyngeal vesicular lesions:
1, herpes labialis: herpes labialis (face herpes) is the most common type of herpes simplex. The cause is infection with herpes simplex virus. It appears that there are hot, itching and flushing in the beginning, and then there are dense integrated groups or groups of needle-sized blisters, which are smaller and more clustered than the original blister, ruptured and eroded, exudate, and gradually dry. Hey, after about 1 to 2 weeks, the local pigmentation can be left behind. The damage occurs at the junction of the skin and mucous membranes, such as the corners of the mouth, the lips and the nostrils, and also occurs in the face and lips. Herpes labialis (face herpes) is the most common type.
2. Lip blisters: Most blister formation is a response to exogenous factors that cause skin irritation or other damage, although some may be the result of a disease or other condition. A single blister is often caused by friction or mild burns, typically on the hands, feet or other exposed areas. A bunch of blister may be the result of a severe burn, or a drug, chemical reaction, or autoimmune disease.
Lip blister According to the theory of traditional Chinese medicine, this disease is indeed a hot certificate, or there is heat inside, or external heat evil, leading to heat poisoning, steaming on the head or bet on the second yin, so it is called "Heat sores" or "fire acne".
The pathogenic effect of BV on humans is much stronger than that on monkeys. The incubation period after virus infection is 2 days to 10 years, and once the disease occurs, the situation is serious. Local skin appears erythema, induration, blister formation after 1 to 3 days; systemic symptoms, including fever, flu-like syndrome, especially headache, myalgia, fatigue, etc., lymphadenitis, lymphangitis, oropharynx Blisters and the like. BV infectious encephalitis can occur even if the condition continues to worsen, and even life-threatening.
Recently exposed to infected monkeys, typical lesions in the infected area, with the symptoms of systemic "flu-like syndrome", that is, the possibility of considering the disease; if BV is isolated from the patient's blister fluid, tissue homogenate, or detected from the patient's serum A specific antibody can be used to make a diagnosis.
The isolation of BV from patient blister fluid, tissue homogenate, or the detection of specific antibodies from patient sera is helpful in diagnosis.
