premature aging
Introduction
Introduction Pathological aging, that is, due to internal or external causes of pathological changes in the human body, causing premature aging, premature aging, this aging is also known as premature aging. Aging is a comprehensive manifestation of the decline and disorder of physiological functions of the body during degeneration, and is an irreversible life process. The human body is organized by cells, and the chemical substances that make up the cells are constantly damaged by the internal and external environment during exercise, causing functional degeneration and aging. Cell aging and death are natural phenomena of metabolism.
Cause
Cause
Cellular aging is an objective reality. Like metabolism, cell aging is an objective law of cell life activity. For multicellular organisms, aging and death of cells and the aging and death of the body are two different concepts. The aging of the body does not equal the aging of all cells, but the aging of cells is closely related to the aging of the body.
The dysfunction of cells under normal environmental conditions gradually leads to death. Aging is a universal law in the biological world. As the basic unit of biological organisms, cells are also constantly dying and dying. Aging is a process. The length of this process is the life of the cell. It varies with the type of tissue and is also affected by environmental conditions. Higher action somatic cells have the largest number of divisions, and cell division will die once this number is reached. The maximum number of divisions of cells in various animals varies from 50 to 60 times. In general, the maximum number of divisions in a cell is directly proportional to the average lifespan of the animal. When the cells are aging, there will be a series of changes such as water reduction, accumulation of senile pigment-lipid pigment, decrease of enzyme activity, and slowing of metabolic rate. There are many hypotheses about cell aging, including genetic factors, cell damage theory, and biological macromolecule aging theory, but they cannot solve the problem satisfactorily.
Through the study of cell aging, we can understand some rules of aging, which are important for understanding aging and finally finding ways to delay aging. The problem of cellular aging is not only a major biological problem, but also a major social problem. With the development of science, the aging process is constantly being clarified, and the average life expectancy of human beings will continue to increase. However, there will be corresponding problems of aging society and the rising incidence of senile diseases such as cardiovascular disease, cerebrovascular disease, cancer and arthritis. Therefore, the study of aging is an important topic in life science research in the future.
Examine
an examination
Related inspection
Urine routine blood routine routine routine physical examination serum glutathione peroxidase
Studies have shown that the nucleus, cytoplasm and cell membrane of aging cells have significant changes:
1 The intracellular water is reduced, the volume is reduced, and the metabolic rate is slowed down;
2 the activity of the enzyme in the cell is decreased;
3 The pigment in the cell will accumulate;
4 The intracellular respiration rate is slowed down, the nuclear volume is increased, the number of mitochondria is decreased, and the volume is increased;
5 cell membrane permeability function changes, so that the material transport function is reduced.
Diagnosis
Differential diagnosis
Studies have shown that modern humans face three kinds of aging: the first is physiological aging, which refers to the physiological deterioration that occurs with age, which is the universal law of all living things.
The second type is pathological aging, which causes pathological changes in the human body due to internal or external causes, causing aging to occur in advance. This aging is also called premature aging.
The third type is psychological aging. Psychological activities are more advanced forms of physical movements of physiological activities. For various reasons, humans often produce the mental state of premature aging and affect the overall function of the body.
