bone marrow transplant

A type of organ transplant that replaces normal bone marrow into a patient's body by intravenous injection to replace the diseased bone marrow. It is used to treat hematopoietic dysfunction, immune function defects, hematological malignancies and other malignant tumors. This treatment can improve the curative effect, improve the prognosis, and obtain long-term survival and even cure. Treatment of diseases: leukemia Indication 1, hematological malignant diseases: various acute and chronic leukemia, myelodysplastic syndrome, malignant histiocytosis, lymphoma, multiple myeloma. 2, non-hematological malignant diseases: breast cancer, ovarian cancer, lung cancer, neuroblastoma and other solid tumors. 3, non-malignant diseases of the blood system: aplastic anemia, paroxysmal nocturnal hemoglobinuria, hemoglobin disease (thalassemia, etc.). 4. Immune system diseases: congenital immunodeficiency disease (SCID), autoimmune disease (SLE, etc.), radiation sickness, etc. Contraindications 1. pregnant women; 2. Rabbit protein allergy; 3. Those with severe platelet deficiency (eg, the number of platelets per ml is less than 50,000); 4. Bacterial, viral or fungal infections have not yet been treated with treatment. Preoperative preparation Bone marrow transplantation is a very demanding technique for aseptic processing. Preoperative patients should be fully prepared. Three days before entering the laminar flow chamber, the function tests of all organs should be performed. Oral antibiotics such as ketoconazole and compound sulfamethoxazole that are not absorbed by the intestines should be taken. Shave your hair, trim your nails, bathe and prepare your skin before surgery. Into the laminar flow room, immerse in the 1:200 chlorhexidine solution for 30 minutes, and carefully scrub the whole body with a small towel. Focus on scrubbing the external ear canal, nostrils, armpits, umbilicus, perineum, toe seams and other skin wrinkles. After the medicated bath, wear sterile underwear, hats, masks, socks and isolation coats. Every time you enter a room, take off a layer, and wear the prepared patient's underwear into the laminar flow room, and then do the bacterial culture of the swabs on the body surface. complication Long-term immunodeficiency.