skin lymphoma
Introduction
Introduction to cutaneous lymphoma Lymphocytomacutis is also known as Spiegler-fendt sarcoma, Spiegler-fendt pseudolymphoma or Bäfverstedt BenignaCutisof Bäfverstedt. The clinical manifestations of the disease are red nodules, which are benign. It is currently believed that the disease is essentially reactive lymphocyte proliferation. basic knowledge The proportion of illness: 0.005% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
Cause of skin lymphoma
Skin lymphoma is a localized excessive immune response to certain stimulating factors, including tattoos, insect bites, trauma, Borrelia burgdorferi infection, immunization, and certain medications.
Prevention
Skin lymphoma prevention
The cause is still unclear, to understand the risk factors of tumors, and to develop appropriate prevention strategies to reduce the risk of cancer. There are two basic clues to prevent tumors. Even if tumors have begun to form in the body, they can help the body to improve resistance. The current focus of cancer prevention and treatment work should focus on and improve those factors that are closely related to our lives, such as Quit smoking, eat properly, exercise regularly, and lose weight. Anyone who follows these simple and reasonable lifestyles can reduce their chances of developing cancer.
Complication
Skin lymphoma complications Complication
I. Infection: refers to the local tissue and systemic inflammatory reactions caused by the invasion of pathogens such as bacteria, viruses, fungi, and parasites into the human body. A psychological infection is a way to cause the same emotions and actions of others. It is essentially the transmission and communication of emotions and plays a big role in interaction.
Second, distant metastasis: refers to the tumor cells invading the lymphatic vessels from the primary site, blood vessels or other pathways are taken to continue to grow, forming the same type of tumor as the primary site tumor, this process becomes metastasis, the formed tumor Become a metastatic tumor or metastatic cancer. Metastasis is a feature of malignant tumors.
Symptom
Symptoms of cutaneous lymphoma, common symptoms, nodular papules
There are two types of localized or disseminated, limited, single or firm nodules or groups of nodules with large or large peas, mainly in the face, especially the forehead and earlobe, nodular surface Usually smooth, flesh-colored, light red, yellowish brown or purple, occasionally nodules also occur in other parts of the body, women are the most common, no visceral damage or blood changes, usually skin lesions in a few months, sometimes 1 to 2 years later Self-resolving, disseminated more common in middle-aged adults, miliary papules or large and hard nodules, mainly in the face, trunk and limbs, damage can last for many years, but can subside, some cases, only long-term follow-up, no Lymphoma and visceral damage can develop to rule out lymphoma.
Examine
Examination of cutaneous lymphoma
Histopathological examination of lesions revealed dermal nodular or diffuse lymphocytic infiltration with tissue cells, rare plasma cells and eosinophils. In some cases, there is a germinal center with a lymphoid follicular-like structure.
The immunophenotype of infiltrating cells is T and B lymphocytes mixed, mainly T cells or B cells. In rare cases, the disease can be converted to cutaneous lymphoma.
Diagnosis
Diagnosis and differentiation of skin lymphoma
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
It should be differentiated from cutaneous lymphoma, cutaneous leukemia, mycosis fungoides, lymphocytic infiltration of the skin and pleomorphic rash. The disseminatedness should be differentiated from sarcoidosis, lupus vulgaris, lupus moss, and skin leukemia.
