Pigmented skin disease

Introduction

Introduction to pigmented skin disease A change in skin color caused by a decrease or increase in pigmentation is called a pigmented skin disease. The disease with reduced pigmentation is caused by melanin deficiency, whitening of whole body or local skin, such as vitiligo; melanin diseases caused by hyperpigmentation or sputum cell growth, such as freckles or pigments. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific population Mode of infection: non-infectious Complications: pigmented nevus pigmentation

Cause

Causes of pigmented skin diseases

1. The content of melanin and carotene increases or decreases beyond the normal range;

2. Melanocytes cannot migrate to the epidermis: such as blue sputum;

3. Reduced synthesis of melanin particles caused by tyrosinase disorders: such as phenylketonuria, albinism;

4, endocrine diseases affect melanin synthesis: such as: Addision's disease;

5, epidermal melanocyte loss: such as vitiligo;

6, excessive proliferation of melanocytes: benign such as freckles, malignant such as malignant melanoma;

7, pigmentation after inflammation: such as lichen planus, eczema and so on.

Prevention

Pigmented skin disease prevention

1. Pay attention to the replenishment of trace elements in the body and promote the use of copper tableware.

2, eat more fresh, light chlorophyll-rich vegetables, eat more pig liver, lean meat, beef, black food such as black sesame, black beans and so on.

3, eat less irritating food, such as wine, pepper, raw garlic and so on.

4, eat less lamb, fat, seafood and so on.

5, eat less carbonated beverages rich in vitamin C, etc.

Complication

Pigmented skin disease complications Complications

According to the morphology, location, extent and treatment response of white spot, it is clinically divided into four types:

1, limited type, white spot single or clustered in a certain part;

2, loose hair, white spots scattered, different sizes, more symmetrical distribution;

3, the general hairstyle, often developed from the above two types, the lesion area is larger than 1/2 of the body surface;

4, segmental type, white spots are distributed according to the nerve segment or dermatomes. According to the condition of pigment loss in the lesion, the disease can be divided into two types: complete type and incomplete type. The former was negative for dihydroxyphenylalanine (DOPA), melanocytes disappeared, and the treatment response was poor. The latter is positive for DOPA, the number of melanocytes is reduced, and the chance of cure is large.

Symptom

Symptoms of pigmented skin disease Common symptoms Skin pigmentation deepens skin blackening itching skin blackening skin pale skin pattern

Skin lesions are limited detachment spots of different sizes, such as porcelain white, the boundary is clear, the edge pigment is thicker than normal skin color, and there is often a temporary inflammatory halo around the new hair lesion. The number of lesions can be single or multiple, and can be melted into pieces. White spots vary in size and shape. The affected area can be white. Generally no consciousness. All parts of the body can occur, usually in the back of the finger, wrist, forearm, face, neck and perineum, around the external genitalia. It can be symmetrically distributed or distributed along the nerve side, in segments or bands.

Examine

Examination of pigmented skin diseases

Histopathological examination was similar to progressive pigmentary purpuric dermatosis, moderate lymphocytic infiltration of the upper dermis and hemosiderin deposition; small vessel dilatation; endothelial cell proliferation.

Diagnosis

Diagnosis and differentiation of pigmented skin diseases

Skin diseases are skin infections and allergic dermatitis, but with age-related degenerative changes in the elderly, skin cancer, which is represented by malignant blackness, is also an important skin disease. Various skin disorders that cause side effects from disease. China has a large population and many patients suffering from skin diseases.

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