Moderate fatty liver
Introduction
Introduction to moderate fatty liver There are many symptoms of fatty liver. The specific manifestations vary according to the severity of the disease. The symptoms of fatty liver are as follows: light-moderate fatty liver often has no symptoms, or occasionally feels liver discomfort, liver function. Only mild abnormalities make it difficult to attract attention and ignore treatment. Moderate-to-severe fatty liver often has symptoms such as abdominal distension, fatigue, severe pain or tenderness in the right upper quadrant, fever, and leukocytosis. The symptoms of fatty liver are not more obvious than other diseases. We should pay more attention to our daily life. It is best to go to the hospital for a physical examination every time to achieve early detection and early treatment. basic knowledge The proportion of illness: 1.5% Susceptible people: good for middle-aged and older people, more men than women Mode of infection: non-infectious Complications: liver cirrhosis liver damage liver and kidney syndrome
Cause
Moderate fatty liver disease
One of the causes: long-term alcohol abuse is the first killer to damage the liver.
Cause 2: Overnutrition Long-term intake of excessive animal fats, vegetable oils, proteins and carbohydrates.
The third cause: malnourished obesity is easy to get fatty liver, but it does not mean that thin people will not get fatty liver.
The fourth cause: diabetes, hepatitis, hyperthyroidism, severe anemia and other chronic diseases. Diabetes patients have two times more fatty liver due to insulin than those without diabetes.
The fifth cause: drug-induced liver damage Drug-induced liver damage accounts for 1/10 of adult hepatitis, and fatty liver is a common type. There are dozens of drugs related to fatty liver, such as tetracycline, acetyl salicin, glucocorticosteroids, synthetic estrogen, amiodarone, nifedipine, certain anti-tumor drugs and lipid-lowering drugs, etc., can lead to fat in Accumulation in the liver.
Cause 6: Hyperglycemia Hypercholesterolemia is closely related to fatty liver. Among them, high TG (triglyceride) is most closely related, most of which are often accompanied by obesity, diabetes and alcoholism. In addition, certain industrial poisons such as yellow phosphorus, arsenic, lead, copper, mercury, benzene, carbon tetraoxide, etc. can also cause fatty liver. Pregnancy, genetic or mental, psychological and social factors, such as sitting, less activities, lazy life, etc. are also related to fatty liver.
Prevention
Moderate fatty liver prevention
1, must stop drinking, eat more vegetables, eat more fruits.
2, control energy intake: for fatty liver patients, energy supply should not be too high. Fatty liver patients who are engaged in mild activities and whose body weight is within the normal range should be supplied with 126-147KJ (30-35kcal) per kilogram per day to prevent weight gain and avoid aggravation of fat accumulation. For obese or overweight, the daily dose should be 84 ~ 105KJ (20 ~ 25kcal) to control or lose weight, to achieve the ideal or appropriate weight. Reasonable diet to prevent fatty liver, eat some coarse grains, do not eat more sweet.
3, in the diet, you can use the food color to match the liver diet. The daily three meals must be properly formulated to achieve a balanced nutrient balance, and a sufficient amount of protein can remove liver fat.
4, the use of drugs with caution The liver is the chemical plant of the human body, any drug into the body must be detoxified by the liver. So don't take medicine if you don't move. For patients with symptomatic fatty liver, it is necessary to carefully guard against the toxic and side effects of drugs when using drugs. Drugs that are harmful to the liver must not be used to avoid further aggravation of liver damage.
5, control carbohydrates: should eat low-carbohydrate diet, fasting foods rich in monosaccharides and disaccharides, such as high-sugar cakes, ice cream, dried dates and sweets, etc., to promote liver fat elimination. However, excessive restriction of carbohydrates can reduce the body's sensitivity to insulin. Daily carbohydrates are about 60% of the total energy.
6, add enough dietary fiber: dietary fiber can slow down the gastric emptying time, reduce the intake and absorption of fat and sugar, with blood lipids, lowering blood sugar.
7, add enough vitamins, minerals and trace elements: the liver stores a variety of vitamins.
Complication
Moderate fatty liver complications Complications liver cirrhosis liver injury liver and kidney syndrome
1, often accompanied by other manifestations of alcoholism, such as alcohol dependence, pancreatitis, peripheral neuritis, anemia, glossitis, alcoholic hepatitis, cirrhosis and so on.
2, over-nutrition fatty liver often management other basic diseases occur, such as obesity, diabetes, hyperlipidemia, hypertension, coronary atherosclerotic heart disease (referred to as coronary heart disease), gout, cholelithiasis and so on.
3, malnutrition fatty liver often coexist with chronic wasting diseases, such as tuberculosis, ulcerative colitis.
4, acute fatty liver in pregnancy often complicated by renal failure, hypoglycemia, pancreatitis, sepsis, disseminated intravascular coagulation (DIC).
Symptom
Moderate fatty liver symptoms Common symptoms Loss of appetite, dyspepsia, diarrhea, vomiting, nausea
Patients with moderate fatty liver manifest as loss of appetite, indigestion, diarrhea and other gastrointestinal symptoms. A large amount of fat infiltrate the liver for a long time, which can cause chronic inflammation of liver cells. Once there are symptoms, the liver has different degrees of inflammation, necrosis and fiber. Chemical. Mild abnormal liver function, fat content is 10% to 25% of liver weight, transaminase, bilirubin mild or moderate increase, and often accompanied by steatohepatitis, B echo in the front half of the liver is thick and strong, The echo in the posterior half of the liver section was significantly reduced, and the light band on the liver surface was reduced.
Moderate to severe fatty liver may have symptoms such as loss of appetite, bloating, fatigue, fever, nausea, vomiting, weight loss, right upper quadrant tenderness or snoring pain. Mild swelling of the liver can be tender, and a small number of patients can have splenomegaly and liver palm.
When there is too much fat deposition in the liver, the liver capsule can be inflated and the liver ligament can be pulled, causing severe pain or tenderness in the right upper quadrant, snoring pain, fever, and leukocytosis. These symptoms are easily misdiagnosed as acute abdomen, so It is differentiated from diseases of the liver and gallbladder system, such as acute hepatitis, chronic hepatitis, cirrhosis, acute and chronic gastritis. To confirm the diagnosis and timely symptomatic treatment.
Examine
Moderate fatty liver examination
Blood biochemical examination: Fatty liver due to hypertrophic fat cells compressing the biliary tract, sometimes elevated serum transaminase, beta globulin, ferritin, apoA, and bile acid are often elevated. Clinical studies have found that only 20%-30% of fatty livers have one or more of the above serological abnormalities and are not specific.
B-ultrasound examination: due to the fat deposition in the liver cells, the ultrasonic energy absorption is obvious, and the scattering effect is generated, so the sound energy is mainly absorbed by the liver front site, and the sound energy of the back field is obviously attenuated, and the structure of the intrahepatic pipeline becomes thin. B-ultrasound can detect fatty liver with liver fat content of more than 30%, and its sensitivity to fatty liver with liver fat content of more than 50% is 100%.
CT examination: diffuse fatty liver showed that the intrahepatic density was generally lower than that of the spleen, kidney and intrahepatic blood vessels. The enhanced intrahepatic vascular image showed very clear, and its morphology was normal. There was a significant negative correlation between the CT value and the amount of liver fat deposition. Ct can show the fat infiltration of the liver because the density is higher than the density of all soft tissues. The mechanism may be that the absorption of fat on the X-ray is reduced, indicating a low-density area, and the intravascular vascular structure is more absorbed by the X-ray amount, thereby showing a dendritic high-density area. For the examination of fat infiltration, although Ct is superior to B-ultrasound, it is still difficult to distinguish from liver cancer with prototype or small-like fat infiltration less than 2 cm in diameter.
Radionuclide: Radionuclide can also be used for the diagnosis of fatty liver, but lacks specificity. It is worth noting the focal fatty infiltration in the liver. B-ultrasound can be a localized placebo, while radionuclide shows normal. To help diagnose.
Liver biopsy: Ultrasound-guided liver biopsy tissue cytology is the main method for the diagnosis of fatty liver. The morphological examination makes necessary special staining, immunohistochemistry, tissue biochemical assay and special cytology examination to improve the diagnosis. accuracy.
Diagnosis
Diagnosis of moderate fatty liver
The upper abdominal symptoms of fatty liver are mainly characterized by special discomfort in the upper abdomen. The main symptoms are liver enlargement, pain or tenderness in the liver area, leukocytosis, fever, dizziness, slow pulse, and salivation. These symptoms are early symptoms of fatty liver. Performance.
Spider mites are one of the early symptoms of fatty liver. They occur in the liver's ability to reduce the fire-fighting ability of estrogen in the body. The occurrence of spider mites may occur in acute and chronic hepatitis, fatty liver or cirrhosis.
Vitamin deficiency is one of the early symptoms of fatty liver, mainly manifested as peripheral neuritis, angular cheilitis, glossitis, hyperkeratosis and other symptoms.
