mild fatty liver
Introduction
Introduction to mild fatty liver Fatty liver production is caused by hepatocyte cytoplasmic changes and excessive fat accumulation. A variety of internal and external causes of fat accumulation in the liver, the liver fat content of more than 5%, medically known as fatty liver. The liver is an important digestive organ of the human body. It plays an important role in the digestion, absorption, oxidation, decomposition, synthesis and transport of fat and maintains its dynamic balance. The fat is absorbed and converted for energy in the body. However, if the fat intake is excessive, the liver's load will be aggravated, resulting in damage to the liver cell membrane, reducing various functions of the liver, causing excessive accumulation of fat and causing fatty liver. basic knowledge The proportion of illness: 0.005%-0.008% Susceptible population: obese, long-term drinking, high-calorie food intake Mode of infection: non-infectious Complications: fatty liver tongue glossitis
Cause
Mild fatty liver disease
Dietary factors
When the nutrient intake exceeds the normal calorie needs of the human body, the excess nutrients become fat and are stored. Long-term accumulation can cause mild fatty liver and obesity. The treatment of mild fatty liver should reduce food intake and reasonable diet.
Mainly caused by long-term heavy drinking. Alcohol has certain toxicity to liver cells, which can cause catabolism of fatty acids and cause accumulation of fatty acids in the liver. At the same time, alcohol can also affect the metabolism and utilization of fat by liver cells, leading to fatty liver. Treatment of mild fatty liver should reduce alcohol intake.
Long-term consumption of carbohydrates or long-term lack of protein intake, resulting in abnormal liver fat metabolism. The treatment of mild fatty liver should be a reasonable diet to meet the health needs of the body.
Disease factor
Hepatitis causes massive destruction of liver cells and damage to liver function, causing the liver to lose balance with fat metabolism. In addition, the diet of patients with liver disease is unreasonable, excessive supplementation, and less activity, resulting in a large accumulation of fatty fat in the liver to form mild fatty liver. The treatment of mild fatty liver requires a combination of multiple methods, a reasonable diet, and increased exercise.
Prevention
Mild fatty liver prevention
The health crisis caused by fatty liver cannot be ignored, so it is important to prevent fatty liver.
The study found that one-fifth of patients with fatty liver will be converted to cirrhosis, because fatty liver affects liver metabolism and causes inflammation of liver cells, and if it continues to deteriorate, it will evolve into liver fibrosis, cirrhosis, and even liver cancer.
Fatty liver patients need to calculate the calories of food before eating and eating, and eat more fruits and vegetables rich in dietary fiber to gain satiety and thus inhibit the absorption of excessive heat, and avoid excess heat into fat accumulation in the liver. In addition to dietary fiber, antioxidant nutrients should be taken, because in the process of liver metabolism, nutrients such as vitamins A, C, E and B are needed to reduce excessive oxidation of fat.
Eating a high nutrient density of fruits and vegetables can help prevent fatty liver.
Complication
Mild fatty liver complications Complications, fatty liver glossitis, angular keratitis
Mild fatty liver patients also often have changes in peripheral neuritis such as glossitis, angular cheilitis, skin ecchymosis, numbness of the limbs, and paresthesia of the extremities. A small number of patients may also have gastrointestinal bleeding, bleeding gums, and nasal discharge. Patients with severe fatty liver may have ascites and lower extremity edema, electrolyte imbalance such as low sodium, hypokalemia, etc., fatty liver manifestations are diverse, in the case of difficult diagnosis, liver biopsy can be diagnosed.
1. Hepatic encephalopathy: symptoms such as drowsiness, abnormal behavior, and coma may occur.
2, kidney failure: may have oliguria, no urine, edema, increased serum creatinine and other performance.
3, diffuse intravascular coagulation: manifested as skin and mucous membrane bleeding points, nose bleeding, gastrointestinal bleeding, etc., through the test can help diagnose.
4, cerebral edema and cerebral palsy: headache, disturbance of consciousness, neck resistance and other high intracranial pressure.
Symptom
Mild fatty liver symptoms Common symptoms Loss of appetite, fatigue, nausea and vomiting, liver enlargement
1. Loss of appetite, fatigue, discomfort or pain in the liver area
This is a symptom often associated with patients with liver disease. If the patient suffers from loss of appetite, fatigue, oiliness, bloating, pain in the liver area, etc., the cold, acute gastritis and other liver diseases are excluded, and the possibility of fatty liver should be suspected.
Second, nausea and vomiting
Nausea and vomiting are common clinical symptoms. If fatty liver is accompanied by liver damage, it may be accompanied by liver symptoms such as nausea, nausea, bloating, and upper abdominal distension. Nausea is often a pre-existing sensation of vomiting, but it can also occur alone, mainly as a special discomfort in the upper abdomen, often accompanied by symptoms such as dizziness, runny, slow pulse, and decreased blood pressure. Vomiting is a complex reflection of the contents of the stomach or a portion of the small intestine that flows back into the mouth through the esophagus. Hepatobiliary and gastric diseases are often accompanied by symptoms of nausea, vomiting or vomiting, such as acute hepatitis, chronic hepatitis (type B, type A, etc.), cirrhosis, acute and chronic gastritis.
Third, liver enlargement
Fatty liver is a common manifestation of liver enlargement. If the liver capsule is stretched, the liver ligament is pulled, the fat cyst is ruptured or inflamed, liver pain and tenderness can be seen, accompanied by rebound pain, fever, and leukocytosis.
Hepatomegaly in patients with fatty liver: about 90% of patients have liver dysfunction, 30% mild hepatomegaly. If liver fat storage accounts for more than 40% of liver weight, it may have obvious hepatomegaly, but it is painless. . Although the liver is swollen, its shape remains normal. If the liver is checked, its texture is normal or slightly soft. And if the surface is smooth and not tender, the possibility of fatty liver should be considered. However, because fatty liver is soft in texture, it is often difficult to palpate even if it is swollen under the abdominal wall.
Hepatic enlargement can be caused by a variety of diseases, and should be diagnosed by combining symptoms, laboratory tests, imaging examinations (B-ultrasound, CT, etc.). If there are obesity caused by excessive nutrition, chronic alcoholism, diabetes, chronic tuberculosis, and various serious anemias, it can help determine whether you have fatty liver. Hepatomegaly is also more common in various types of viral hepatitis, liver tumors, amoebic abscess, cirrhosis, liver tuberculosis, etc., so the diagnosis should also be combined with symptoms, laboratory tests, imaging examinations (B-ultrasound, CT, etc.) Confirmed diagnosis.
Fourth, spider mites
Spider mites are vasospasm formed by the branching expansion of the small arterioles of the skin. They are shaped like spiders, so they are called spider mites. The occurrence of spider mites is generally thought to be related to the weakening of the inactivation of estrogen in the liver by the liver.
Spider mites appear in areas of the superior vena cava, such as the face, neck, back of the hand, upper arm, chest and shoulders. The size of the cockroaches varies, and the diameter can be as large as a few centimeters. During the examination, the center of the iliac crest (ie, the central small arteries cadre) is pressed with a fingertip or a (needle) matchstick. The radial small vascular network is discolored, and reappears after the pressure is removed.
Spider mites are common in acute and chronic hepatitis, fatty liver or cirrhosis. Chronic liver disease (including fatty liver) patients often have redness in the palm-sized fish. If the color is faded after pressing, it is called liver palm, and the mechanism is the same as that of spider. According to reports, 270 patients diagnosed with fatty liver in liver biopsy had spider mites, spider mites disappeared after fatty liver improved, and 3 patients changed from fatty liver to cirrhosis, and spider mites increased.
Fifth, endocrine disorders
The liver is a place where many endocrine hormones are inactivated. In the case of fatty liver, in addition to spider mites, there may be male breast development, testicular atrophy, impotence, female menstruation, amenorrhea, and weight loss or increase of the patient.
The mechanism of patient weight change is thought to be that the inactivation of cortisol in the liver is reduced, resulting in an increase in the amount of cortisol in the blood, a change in the basal metabolism of the patient, and a change in body weight. Liver dysfunction, sugar, protein, fat three major metabolic disorders, can also lead to weight loss or obesity.
Six, vitamin deficiency
Fatty liver is prone to multivitamin deficiency due to fat accumulation and vitamin deficiency in the diet. Clinical manifestations of peripheral neuritis, glossitis, angular cheilitis, ecchymosis, hyperkeratosis, etc.
Vitamin deficiency is often thought to be due to insufficient vitamin intake in patients with fatty liver. However, some people think that when liver damage is severe, the vitamin content in liver tissue is also reduced. Therefore, fat accumulation and vitamin deficiency in the diet are symptoms of vitamin deficiency. Two main reasons.
Seven, Huang Wei
Astragalus is caused by the bilirubin metabolism disorder in the body, resulting in increased blood bilirubin concentration, infiltration into tissues, especially the sclera, mucous membranes and skin stained yellow.
Astragalus membranaceus can be divided into three types according to the mechanism of hemolytic, hepatic and obstructive. In the case of fatty liver, the type of jaundice is often hepatic, and this type of jaundice is often accompanied by symptoms such as fatigue, burnout, and loss of appetite. Clinical data show that only a small number of patients with fatty liver have mild jaundice. After the liver fat is cleared, the jaundice subsides.
Examine
Mild fatty liver examination
Laboratory examination: liver function examination, B-ultrasound examination.
Diagnosis
Diagnosis of mild fatty liver
There are many clinical symptoms, and patients are found by chance when they are more than B-ultrasound. Because they are concealed, they are easily overlooked by patients. Some only show fatigue, good appetite, greasy, cholesterol, and triglyceride increase. Liver function is basically normal, the fat content is 5%-10% of liver weight, and 10%-30% fat infiltration in hepatic lobules. Abnormal liver function indicators (transaminase, albumin, alkaline phosphatase, etc.) may occur. B-ultrasound showed a slight thickening and enhancement of the echo in the front of the liver, and the echo in the posterior half of the liver section was reduced, and the liver surface band was present.
