Serum urticaria
Introduction
Introduction to serum urticaria Serum urticaria is due to many drugs such as penicillin, trifluralin, and sulfa drugs. Serum, vaccines, etc. can be caused by allergic reactions, and drugs such as morphine, codeine, and atropine can directly cause the release of mast cells to cause tissue. The patient has fever, joint pain and swollen lymph nodes, and the rash is common with ring winds. When accompanied by impaired renal function, abnormal urine can occur. basic knowledge The proportion of sickness: 0.2% Susceptible people: no specific population Mode of infection: non-infectious Complications: kidney damage
Cause
Serum urticaria cause
The most common cause of this disease is the injection of allogeneic serum or serum preparations (such as tetanus antiserum, etc.) vaccines, biological agents, and sputum, an allergy mediated by the antigen-antibody complex. Patients usually have four syndromes such as fever, rash, joint pain and lymphadenopathy after using sputum, accompanied by obvious systemic symptoms such as fatigue and discomfort. The characteristic rash is characterized by large edema-type erythema and wheal, which are fused together into pieces and consciously itching or burning. If you do not take timely and effective treatment, it may involve the kidneys or heart.
Prevention
Serum urticaria prevention
1. Screen allergens and stay away from allergens.
2. Avoid entering various serum and protein products.
Complication
Serum urticaria complications Complications kidney damage
If the disease is not treated promptly and effectively, it may involve the kidneys or heart.
Symptom
Serum urticaria symptoms Common symptoms Windy skin rash Skin itching Lymph node swelling Fatigue fever with joint swelling and pain
Clinical manifestations:
There is a rapid appearance of the wind rash block (wind group), and it is often itchy or tingling in the local area a few minutes before the appearance of the rubella block. Some patients have systemic symptoms such as poor appetite, general malaise, headache or fever in the rubella block for a few hours or a day or two.
The rubella is flat reddish or pale yellow or pale edematous plaque with a reddish edge. Sometimes, the rubella block is ring-shaped and can be called a ring-shaped urticaria. Several adjacent ring-shaped lesions can be connected or fused to form a map, which can be called a graphic urticaria. Sometimes, there is a stasis in the center of the lesion, which can be called hemorrhagic urticaria, and the kidney and the gastrointestinal tract can bleed at the same time. When there is a blisters in the rubella block, it is called vesicular urticaria. When there is a bullous, it is called bullous urticaria. Sometimes, blisters or bullae occur on seemingly normal skin, but often have a blush, which is more likely to occur in children.
Rubella blocks often disappear within a maximum of 1-2 days in one or two hours or a few hours, but new lesions often appear in other places, and the rubella blocks have disappeared within 24 hours. After the rubella block disappears, the skin returns to normal, and sometimes there are temporary pigment spots called hyperpigmented urticaria. The size and number of rubella blocks may vary from skin to mucous membranes in any part. Rubella block causes itching, acupuncture or burning sensation, but the degree of each person is different. Severe patients have systemic symptoms such as headache and fever. Especially patients with acute urticaria can have fever up to 40 °C, blood pressure can be reduced or even fainting and shock can occur. It must be treated promptly. Most patients have only itchy rubella and no other symptoms.
Examine
Examination of serum urticaria
an examination:
1, blood routine.
2, when the kidney injury occurs, check the urine routine.
3. Screening of allergens.
4. Examination of skin wheal.
Diagnosis
Diagnosis and identification of serum urticaria
diagnosis:
Due to the application of allogeneic serum, including various anti-toxic serum, vaccine, gamma globulin or albumin, blood transfusion and other serum or its products and blood supplied by humans or animals. Occurrence of erythema, itching, and wheal at the injection site or throughout the body, as well as ring erythema and nodular erythema. In addition, about 2.7% of patients may also have systemic symptoms such as fever, lymphadenopathy, myalgia, joint pain, cyanosis, and hypocomplementemia, called serum disease, whose symptoms are self-limiting and gradually disappear. However, there are also a few severe cases that can cause death.
