small cornea
Introduction
Introduction of small cornea The small cornea is a congenital dysplasia. It is autosomal dominant or recessive. Can be single eye or both eyes, no gender difference. The flat diameter of the cornea is less than 10 mm, the radius of curvature is increased, the anterior segment of the eye is disproportionately reduced, and the size of the eyeball can be normal. Often accompanied by a variety of congenital anomalies in the anterior segment of the eye, the visual effect can be seriously impaired. If there are no other abnormalities, the visual acuity is better. In addition, the shallow anterior chamber is often accompanied by angle-closure glaucoma. The small cornea is mostly part of the small eyeball. The cornea diameter is reduced. The boundary of the corneoscleral transition is clear. Often combined with iris choroidal defects, eyeball tremors and so on. It is prone to glaucoma. basic knowledge Sickness ratio: 0.0012% Susceptible people: no special people Mode of infection: non-infectious Complications: glaucoma
Cause
Small corneal cause
Cause:
Caused by autosomal dominant or recessive inheritance. It is a congenital disease. Autosomal dominant inheritance refers to a hereditary disease in which a defective gene is dominantly expressed and 50% of children have an onset probability. Autosomal recessive inheritance is an autosomal recessive disorder in which a person must have two copies of an abnormal allele. In some populations, there may be a high proportion of heterozygotes or carriers due to the founder effect ( The population has few members at the time of its origin, one of whom is a carrier), or because the ancestors gave the carrier a choice advantage (for example, in sickle cell anemia, heterozygous individuals do not develop malaria).
Prevention
Small corneal prevention
Improve prenatal diagnostic techniques, prevent the birth of genetic children, and improve the eugenic rate.
Complication
Small corneal complications Complications glaucoma
The small cornea is mostly part of the small eyeball. The cornea diameter is reduced. The boundary of the corneoscleral transition is clear. Often combined with iris choroidal defects, eyeball tremors and so on. It is prone to glaucoma. Some people think it is a recessive genetic disease.
Symptom
Small corneal symptoms Common symptoms Visual impairment Corneal opacity Corneal ulcer Corneal foreign body
The flat diameter of the cornea is less than 10 mm, the radius of curvature is increased, the anterior segment of the eye is disproportionately reduced, and the size of the eyeball can be normal. Often accompanied by a variety of congenital anomalies in the anterior segment of the eye, the visual effect can be seriously impaired. If there are no other abnormalities, the visual acuity is better. In addition, the shallow anterior chamber is often accompanied by angle-closure glaucoma. The small cornea is mostly part of the small eyeball. The cornea diameter is reduced. The boundary of the corneoscleral transition is clear. Often combined with iris choroidal defects, eyeball tremors and so on. It is prone to glaucoma. Some people think it is a recessive genetic disease.
Examine
Small cornea examination
Ophthalmic examination, fundus fluorescein examination.
Diagnosis
Small corneal diagnosis
diagnosis
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.
Differential diagnosis
Acute angle-closure glaucoma: examination showed that the cornea was foggy and turbid, and the diameter was generally more than 11 mm. In the severe case, the elastic layer had strips of turbidity and cracks; the anterior chamber was very deep; the pupil was slightly enlarged; the fundus: the late optic disc was pale and It is annularly depressed; the intraocular pressure is very high; the eyeball is enlarged. Acute attack, accompanied by severe headache, nausea, vomiting, etc., sometimes overlooking the symptoms of the eye, and misdiagnosed as acute gastroenteritis or nervous system disease, acute episodes are easy with acute iridocyclitis or acute conjunctivitis Confused.
