Sheehan's Syndrome
Introduction
Introduction to Xi's syndrome Sheehansyndrome, classified as endocrinology by disease. The anterior pituitary gland secretes many hormones such as gonadotropins, thyrotropin, adrenocorticotropic hormone, prolactin, and growth hormone. There is a portal vein connection between the anterior pituitary and the hypothalamus, and the neuropeptide substance secreted by the hypothalamus is accepted. Postpartum hemorrhage easily causes thrombosis in these portal veins, which eventually leads to necrosis of the anterior pituitary gland, and various hormone-promoting levels are greatly reduced. Therefore, thyroid, adrenal cortex, ovary and other dysfunction occur, and even various symptoms mentioned above occur. It is a serious disease. It is important to prevent postpartum hemorrhage. Once hemorrhage occurs after delivery, he should replenish the circulating blood volume in time to avoid the occurrence of shock. basic knowledge The proportion of illness: 0.0003% Susceptible people: good for postpartum women Mode of infection: non-infectious Complications: nausea and vomiting
Cause
Cause of Xi's syndrome
Postpartum hemorrhage and shock (45%):
Xi's syndrome is caused by postpartum hemorrhage, shock, causing pituitary ischemia and necrosis, resulting in ovarian dysfunction, uterine atrophy, secondary amenorrhea, accompanied by hair loss, loss of libido, general malaise and a series of extremely debilitating syndromes .
Damage (30%):
Chinese medicine believes that this disease is mostly due to birth injury, excessive blood loss, blood deficiency, kidney loss, renal reproductive function decline, so that the pulse is impassable, too small pulse of dysfunction and amenorrhea.
Prevention
Xi's syndrome prevention
Sheehan's syndrome is a preventable disease. Doing a good job in perinatal health care, preventing postpartum hemorrhage and preventing and treating shock are the correct measures to prevent this disease. Once hemorrhagic or septic shock occurs, it should be treated in time to reduce bleeding, shorten blood loss time, and timely replenish blood volume, so that the impact of ischemic necrosis can be compensated by compensation.
Complication
Xi's syndrome complications Complications, nausea and vomiting
Physical infection, weight loss, etc.
Symptom
Symptoms of Xi's syndrome Common symptoms Loss of appetite Postpartum no milk secretion body hair loss dizziness Postpartum breast atrophy Postpartum extreme weakness Mane and pubic hair off expression Apathy Skin dry libido
1. Have the primary cause of the disease:
Such as postpartum hemorrhage, pituitary tumors, pituitary surgery or radiation therapy, craniocerebral trauma, infection or inflammation (tuberculosis, syphilis, meningoencephalitis), systemic diseases (leukemia, lymphoma, cerebral arteriosclerosis, malnutrition) and immune pituitary Inflammation and so on.
2. Gonadotropin and prolactin deficiency syndrome
Postpartum no milk, amenorrhea, yin, sputum, eyebrows shedding, sparse, loss of libido, disappearance, external genital atrophy, uterus, breast atrophy.
3. Thyroid stimulating hormone deficiency group:
Less gas lazy words, indifferent expression, mental decline, slow movements, loss of appetite, chills, less sweat, dry skin, swollen facial yellowness, and even mucous edema.
4. Adrenocorticotropic hormone deficiency group:
Dizziness, weakness, nausea, vomiting, abdominal pain, diarrhea, weight loss, blood pressure, infection, syncope and even shock, coma.
5. Pituitary crisis;
If there are various kinds of stress, infection, surgery, trauma, mental stimulation, digestive tract diseases, certain drugs (sedation, anesthetics and hypoglycemic agents), the primary disease can be aggravated and the crisis can be induced.
Examine
Xi's syndrome examination
Hypoglycemia
The glucose tolerance curve is low, or a reactive hypoglycemia curve, which is abnormally sensitive to insulin.
Pleural anterior pituitary hormone
Such as growth hormone (GH), prolactin (PRL), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle stimulating hormone (FSH), luteinizing hormone (LH) and so on are low levels. The pituitary gland does not respond to the stimulation of the hypothalamic release hormone (such as TRH, LHRH stimulation test) or the reaction is mild.
Hypophyseal secretion
Adrenal insufficiency. Serum testosterone, estradiol, thyroid hormone, cortisol levels are reduced, but delayed response to the corresponding exogenous pituitary stimulating hormone (such as the ACTH stimulation test).
Diagnosis
Diagnosis and identification of Xi's syndrome
For Sheen syndrome with typical medical history, symptoms and signs, there is no difficulty in diagnosis. The vast majority of patients have postpartum hemorrhage, shock, postpartum milk-free history and related pituitary hormone deficiency symptoms, but no headache, no visual field defects. According to the history, symptoms, signs and endocrine hormones are low levels, it is not difficult to make a diagnosis.
