lacrimal gland cystoid adenocarcinoma
Introduction
Introduction to lacrimal cystic adenocarcinoma The lacrimal cystic adenocarcinoma is the most common malignant tumor of the lacrimal gland. Occurs in 30-40 years old, women are more common, and the course of disease is short-term. The tumor is round or nodular, and the size is not equal, but the diameter is more than 2 to 4 cm, and the boundary with the surrounding tissue is unclear. The mass is mostly substantial, the texture is slightly hard, and there is no envelope. The cut surface is gray or light yellow, moist, and some microcapsules are visible, and a few are mainly large capsules. Symptoms are marked by significant pain, the eyeball protrudes forward and downward, dyskinesia, often with diplopia and visual impairment. X-ray film or CT scan can show bone destruction. Surgical removal of the tumor, the prognosis of this disease is poor. basic knowledge The proportion of illness: 0.0025% Susceptible people: good for people aged 30-40 Mode of infection: non-infectious Complications: eyeballs
Cause
The cause of lacrimal cystic adenocarcinoma
Primary factor (80%):
The cystic adenoid carcinogenesis of the body's lacrimal gland cells is caused by environmental, physical, chemical, genetic and other factors.
Secondary factors (15%):
The disease is caused by the metastasis of cancer cells caused by cancerous cells in tissues and organs of other parts of the body.
Prevention
Lacrimal gland cystoid adenocarcinoma prevention
There are no effective preventive measures for this disease. Early detection, early diagnosis and early treatment are the key to the prevention and treatment of this disease. Once the disease occurs, it should be actively treated to prevent the occurrence of complications.
Complication
Lacrimal cystic adenocarcinoma Complications
There may be other malignant lesions.
Symptom
Lacrimal gland cystic gland cancer symptoms Common symptoms Eyeball prominent visual impairment Double eyeball can not be free of eye movement
There is obvious pain, the eyeball protrudes forward and downward, the movement is disordered, and there are often diplopia and visual impairment.
Gross shape: The tumor is round or nodular, varying in size, but the diameter is more than 2 to 4 cm, and the boundary with the surrounding tissue is unclear. The mass is mostly substantial, the texture is slightly hard, and there is no envelope. The cut surface is gray or light yellow, moist, and some microcapsules are visible, and a few are mainly large capsules.
Examine
Examination of lacrimal cystic adenocarcinoma
X-ray film or CT scan can show bone destruction.
Microscopic examination
There are two types of tumor cells, namely, ductal lining epithelial cells and myoepithelial cells. There are many arrangements for tumor cells, and a sieve-like structure is a typical image of this tumor. The tumor cells are arranged in a round, oval or irregular epithelial mass containing a plurality of round or oval cystic cavities of varying sizes, which are mesh-like, similar to the cross-section of the tendon. These small cystic spaces are mostly surrounded by neoplastic myoepithelial cells and contain mucus-like substances. Under electron microscopy, the cavity contains a substrate, a star-shaped granular mucus sample and collagen fibers, wherein the collagen fibrils can be glass-like and even occupy the entire capsule cavity to form a transparent protein cylinder.
In adenoid cystic carcinoma, in addition to the sieve-like structure, it can be seen that the tumor cells are densely arranged with solid small strips, small clumps and small duct-like structures. The small catheter-like structure is surrounded by 2 to 3 layers of cells, sometimes containing red stained mucus. Solid adenoid cystic carcinoma is rare, often partly a large solid mass, and some are still sieve-like structures or small strips. Cell degeneration, necrosis and cysticity can occur in the center of large masses. change.
Diagnosis
Diagnosis and differentiation of lacrimal cystic adenocarcinoma
Diagnosis can be made based on clinical manifestations. No need to identify.
