idiopathic obstructive bronchiolitis with organizing pneumonia
Introduction
Brief introduction of idiopathic obstructive bronchiolitis with organizing pneumonia Idiopathic obstructive bronchiolitis with organizing pneumonia (esthetic BOOP) is a special clinical pathological syndrome of unknown etiology, which can develop focal organizing pneumonia, fibrotic granuloma tissue obstructs bronchioles and Alveolar duct. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific population Mode of infection: non-infectious Complications: cryptococcosis lymphoma hypersensitivity pneumonitis
Cause
Idiopathic obstructive bronchiolitis with the cause of organizing pneumonia
As a special clinical pathological syndrome with unknown etiology, it can develop into focal organizing pneumonia, and fibrotic granuloma tissue obstructs bronchioles and alveolar ducts.
Prevention
Idiopathic obstructive bronchiolitis with organizing pneumonia prevention
Because this disease is a special clinical pathological syndrome with unknown etiology, improving the living environment and changing bad habits, such as smoking and drinking, improving autoimmune function, is the key to the prevention and treatment of this disease.
Complication
Idiopathic obstructive bronchiolitis with complications of organizing pneumonia Complications cryptococcal lymphoma hypersensitivity pneumonitis
Can be secondary to other pathological processes, including cryptococcosis, Wegener granulomatosis, lymphoma, hypersensitivity pneumonitis and eosinophilic pneumonia.
Symptom
Idiopathic obstructive bronchiolitis with symptoms of organizing pneumonia Common symptoms Loss of fatigue, leukocytosis, cough, chest pain, fever, cough, sputum... ESR increases fever
Idiopathic obstructive bronchiolitis with organizing pneumonia (esthetic BOOP), or cryptogenic organizing pneumonia involving the same proportion of men and women, usually 40 to 50 years old. Almost 3/4 patients, symptoms lasting less than 2 Months, before the diagnosis, there are very few symptoms more than 6 months. In 2/5 patients, influenza-like illness, manifested as cough, fever, discomfort and weight loss, often indicate the onset of the disease. Chest physical examination often smells and sucks Gas pronunciation.
Examine
Examination of idiopathic obstructive bronchiolitis with organizing pneumonia
Routine laboratory tests are non-specific. About half of the patients have leukocytosis with elevated eosinophils, and the initial erythrocyte sedimentation rate is elevated. Although obstructive disorder can be found in 21% of the cases [forced expiratory volume occupancy in the first second) Percentage of vital capacity (FEV1 / FVC) <70%], and lung function can be normal, but pulmonary function tests often show restrictive disorders. Hypoxemia is common at rest and after exercise.
Chest X-ray showed bilateral diffuse alveolar density with normal lung volume. Shadows were peripherally distributed and could be found to be similar to those characterized by chronic eosinophilic pneumonia. Very rare cases Increased alveolar density is unilateral. Repeated migratory lung shadows are common. Linear or nodular interstitial shadows are rare. Lung HRCT scans show patchy air cavity consolidation, ground-glass shadows Small nodule shadows and thickening and dilatation of the bronchial wall. Patchy shadows are more common in the periphery of the lungs, often at the base of the lungs. CT scans can show a wider range of lesions than chest X-rays.
Lung biopsy showed massive granulation tissue hyperplasia in small airways and alveolar ducts, with chronic inflammation around the alveolar. Focal organizing pneumonia (a type of BOOP) is a non-specific response to lung injury and can be secondary to other pathologies. The process includes cryptococcosis, Wegener granulomatosis, lymphoma, hypersensitivity pneumonitis and eosinophilic pneumonia.
Diagnosis
Diagnosis and differentiation of idiopathic obstructive bronchiolitis with organizing pneumonia
Diagnosis can be based on medical history, clinical symptoms, and laboratory tests. Attention should be paid to the differential diagnosis of tuberculosis, lung tumors and occupational lung disease.
