autoerythrocyte hypersensitivity purpura
Introduction
Introduction to autologous red blood cell allergic purpura Autologous red blood cell allergic purpura, also known as painful recurrent ecchymosis purpura (Gardner-Diamond syndrome), is a rare disease that occurs only in women, more than emotional stress or mental abnormalities, so some people call it " Spiritual purpura." basic knowledge Sickness ratio: 0.0004% Susceptible people: only for women Mode of infection: non-infectious Complications: gastrointestinal bleeding, cerebral hemorrhage, hematuria
Cause
Cause of autologous red blood cell allergic purpura
Causes:
Emotional or mentally abnormal.
Pathogenesis:
Pathological sections of the lesion showed infiltration of neutrophils and eosinophils around the blood vessels, swelling of vascular endothelial cells, or fibrin-like necrosis of capillaries.
Prevention
Self-erythrocyte allergic purpura prevention
1. Keep a steady mood, don't be overjoyed. Treat the blow, no matter what the blow, be calm. You can find a friend to talk about it, you can also take a trip, or read a book to listen to music and other ways to relax yourself, so that the spirit is not so nervous.
2. In terms of diet, eat more food that is easy to digest, and don't eat too much spicy and stimulating things. As a woman, the diet should be as light as possible, do not eat big fish and meat, do not eat greasy, heavy taste. Eat more fruits and vegetables.
3. Don't let yourself stay up all night, pay attention to rest. Women must have enough sleep. If you exercise properly, don't stay at home all day, don't face the computer all day.
Complication
Autologous red blood cell allergic purpura complications Complications, digestive tract bleeding, cerebral hemorrhage
1. Can be complicated by gastrointestinal bleeding, black stools.
2. Combined brain hemorrhage.
3. Combined with kidney damage, hematuria.
Symptom
Symptoms of autologous red blood cell allergic purpura Common symptoms Menstrual volume, fatigue, itching, distress, nausea, abdominal pain, poor urination
Patients may have headache, dizziness, fatigue, diplopia, fever, nausea, vomiting, abdominal pain, difficulty urinating, menorrhagia, etc., mostly after some serious trauma or major surgery, the occurrence of itching, burning, The tingling sensation, redness and ecchymosis appeared after a few hours, the bleeding range expanded rapidly, and the thigh was the multiple site.
Examine
Examination of autologous red blood cell allergic purpura
There is no specific laboratory test for this disease. Patients are allergic to autologous red blood cells. They can make 1% suspension with their own red blood cells (whole blood), take 0.1ml for intradermal injection, and can have a round skin reaction, or make There is pain and swelling in the injection, and some scholars have increased the concentration of their own red blood cell suspension to 20% or even 80%. It is found that the reaction can be initiated within 15 minutes of intradermal injection, and the recurrence of the plaque can be induced within 24 hours. There are also false positive results.
According to the condition, choose B-ultrasound, gastrointestinal endoscopy, head CT and other examinations.
Diagnosis
Diagnosis and identification of autologous red blood cell allergic purpura
The erythema sign of the disease before the ecchymosis, self-erythrocyte intradermal test is helpful for the diagnosis of this disease.
Clinically, it should be differentiated from simple purpura.
