vaginal endometrial stromal sarcoma
Introduction
Introduction to vaginal endometrial stromal sarcoma Vaginal endometrial stromal sarcoma is classified into low-grade malignant and high-grade malignant according to the degree of malignancy. Low-grade malignant endometrial stromal sarcoma has many names in the past. It has been called interstitial endometriosis. Lymphatic mesenteric myopathy, lymphatic mesenchymal dysplasia, interstitial sarcoma or mullerian stromal sarcoma (mullerianstromalsarcoma). basic knowledge The proportion of illness: 0.001% Susceptible people: women Mode of infection: non-infectious Complications: bloating
Cause
Vaginal endometrial stromal sarcoma
Cause:
The tumor tissue is grayish yellow and fishy. When invading the muscle wall locally, it can be a small group of protrusions, and the toughness is rubbery and elastic. Part of the muscle wall is thickened. Visceral plugs can be seen in the blood vessels and are elastic.
Microscopic examination of low-grade endometrial stromal sarcoma cells is similar to normal proliferative endometrial stromal cells, which are filled with thick-walled small blood vessels that secrete late spiral arteries. The cells are round, uniform in size, with little cytoplasm, deep nuclear staining, and mitotic figures like <3/10HPF. Tumor cells invade the lymphatic vessels or blood vessels to form a tumor-like tumor thrombus. Highly malignant cells have atypical atypia, with mitotic figures 10/10 HPF.
Immunohistochemical vimentin and CD10 showed diffuse and strong positive expression. Most of ER and PR were positive and some were desmin positive.
Prevention
Vaginal endometrial stromal sarcoma prevention
1. Reconcile your feelings and get things done.
2. Marry at the right time, have children.
3. Do not abuse hormone drugs.
4. Regularly check the body and find out that the disease is treated early.
5, develop good habits, avoid staying up late, and ensure sleep.
Complication
Vaginal endometrial stromal sarcoma complications Complications
Complications are common in infections after rupture.
Low-grade endometrial stromal sarcoma: low malignancy, good prognosis, but high recurrence rate. Reoperation of recurrent foci can still achieve better curative effect, and the tumor is moderately sensitive to radiation. It is effective for progesterone therapy and chemotherapy. Relapsed patients may still have long-term survival after comprehensive treatment.
Highly malignant endometrial stromal sarcoma: easy to hemorrhagic necrosis and easy recurrence, poor prognosis.
Symptom
Vaginal endometrial stromal sarcoma symptoms common symptoms vaginal posterior vaginal tenderness leucorrhea increased urination is not smooth bloating anal bulging vaginal bleeding nodules difficult bowel movement
Vaginal endometrial stromal sarcoma mostly manifests as nodular vaginal wall nodules, accompanied by vaginal bleeding, increased vaginal discharge, can also be manifested as lower abdominal pain, vaginal, anal bulge, urination, difficulty in defecation, mass size 3 ~ 10cm It can be polypoid, clear border, soft, no tenderness, active or fixed.
Examine
Examination of vaginal endometrial stromal sarcoma
Vaginal endometrial stromal sarcoma examination: immunohistochemistry, histopathology, colposcopy.
Colposcopy: colposcopy is the use of colposcopy under a strong light source, the cervical vaginal epithelium is magnified 10-40 times directly to observe the tiny lesions that are invisible to the naked eye, and the biopsy is performed in the suspicious part. To improve the diagnosis rate of cervical diseases.
Diagnosis
Diagnosis and diagnosis of vaginal endometrial stromal sarcoma
Vaginal endometrial stromal sarcoma can be diagnosed based on clinical symptoms, signs and laboratory tests.
Vaginal endometrial stromal sarcoma should be differentiated from superficial vaginal interstitial reaction and other vaginal tumors.
