pruritic purpura
Introduction
Introduction to itch purpura Itching purpura (ecthingpurpura) is also known as eczema-like purpura or disseminated pruritic angiitis (disseminnatepruriginous angiodermatitis). The etiology of this disease is unknown, and the pathogenesis is still unclear. It may be related to microbial infections in adult males, which occurs in spring and summer. The skin lesions began to appear around the ankle with erythematous erythema and purpura rash with a clear orange border. Then spread up, after a few weeks can affect the calf and the body consciously itching skin lesions with the most serious clothing friction. It needs to be differentiated from drug eruption and progressive pigmentary purpuric skin disease (schamberg disease). Topical application of corticosteroid preparations has an antipruritic effect. Oral administration of prednisone, kabakol (an blood), vitamin C and vitamin K can be effective. basic knowledge The proportion of sickness: 0.01% Susceptible population: more common in adult males Mode of infection: non-infectious Complications: sepsis
Cause
Cause of itch purpura
(1) Causes of the disease
The cause of this disease is unknown and may be related to microbial infection. It may be related to environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. Current research suggests that the disease may be closely related to microbial infections.
(two) pathogenesis
The pathogenesis is still unclear. It is now believed that there is a certain relationship with allergic damage caused by the action of bacterial toxins after infection.
Prevention
Itching purpura prevention
The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. At present, the research suggests that the disease may be closely related to microbial infections. Therefore, clinical prevention is mainly to strengthen exercise and avoid infection of pathogens. At the same time, it can reduce the chance of medication and reduce allergic injury.
Complication
Itching complication Complications sepsis
The disease has obvious pruriticity, and the patient often has a history of scratching. The skin integrity is destroyed due to scratching, so skin bacterial infection or fungal infection may be induced by scratching, usually secondary to low constitution, or long-term use of immunosuppressants. And patients with fungal infections such as onychomycosis, such as concurrent bacterial infections may have fever, skin swelling, ulceration and purulent secretion and other performance. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Itching purpura symptoms common symptoms itching purpura rash
The disease occurs mostly in adult males. It occurs in spring and summer. The skin lesions start around the ankles. Spotted erythema and purpura rash appear orange, with clear boundaries and then spread upwards. After a few weeks, the calves and the whole body can be affected. Consciously itching, skin damage is the most serious rubbing of clothes, but the palm and face are generally not involved, due to severe itching, the skin often occurs lichen-like changes, the course of 3 to 6 months, can relapse.
Examine
Examination of itch purpura
Clinical skin examination: occurs in spring and summer. The skin lesions began around the ankle, with erythematous erythema and purpura rash, orange-yellow and clear borders. Then spread up, after a few weeks can affect the calf and the whole body, consciously itching, the skin damage is the most serious with clothes.
Histopathological examination: similar to progressive pigmented purpuric skin disease, moderate lymphocytic infiltration of the upper dermis and hemosiderin deposition; small blood vessel dilation; endothelial cell proliferation.
Diagnosis
Diagnostic identification of itch purpura
diagnosis
According to this disease, it is more common in adult males. In the season of good hair, the initial site of skin lesions, intense itching and orange color are not difficult to diagnose.
Differential diagnosis
It needs to be differentiated from drug eruption and progressive pigmentary purpuric skin disease (schamberg disease).
1. Drug rash: It does not start around the ankle, there is a history of medication, and the incidence has nothing to do with the season.
2. Schamberg's disease: The course of the disease is longer, and the rash is generally itchy.
