abnormal pancreaticobiliary duct syndrome
Introduction
Introduction to pancreaticobiliary tract abnormal syndrome Abnormal Pancreaticocholang Synoflow Syndrome is also called congenital choledochal cyst. It is an autosomal recessive hereditary disease. Due to the obstruction of bile excretion, the absorption of fat-soluble vitamin K is insufficient, which may cause abnormal clotting process. When there is serious lack of pipeline, it may often manifest as spontaneous bleeding, such as systemic blood stasis. Spot, hematoma, gastrointestinal bleeding, nosebleeds, joints, muscles, intracranial hemorrhage, some patients have frequent abdominal pain, increased pancreatic amylase in the blood and other symptoms of pancreatitis. basic knowledge The proportion of illness: the incidence rate is about 0.005% - 0.008% Susceptible people: no special people Mode of infection: non-infectious Complications: nosebleeds, abdominal pain, intracranial hemorrhage
Cause
Causes of pancreaticobiliary confluence syndrome
Genetic factors (45%):
It is an autosomal recessive hereditary disease. Various biliary and pancreatic diseases caused by abnormal pancreaticobiliary duct have caused clinical attention, but there are different opinions on classification. In 1985, Miyano Takeo proposed a new classification for clinical application. The method can be divided into: type I (long common tube type), which can be further divided into: type Ia - cystic dilatation type, equivalent to congenital common bile duct dilatation (CBDI); type Ib - fusiform dilatation type (CDBII) Type); type Ic - no bile duct expansion; type II, for other complex confluence anomalies.
Body factor (55%):
Due to cholestasis and varying degrees of liver dysfunction, coagulation factors II, VII, IX, X, etc., collectively referred to as vitamin K-dependent factors, are synthesized in hepatocytes, and approximately 1 in 6 patients may have spontaneous perforation of the common bile duct. The cause of perforation may be spontaneous perforation of the common bile duct. The reason for perforation may be congenital weakness of the common bile duct wall, narrow end, distortion caused by bile excretion or secondary infection, malformation of pancreaticobiliary junction, pancreatic juice reflux, intra-biliary pressure It is too high.
Prevention
Prevention of pancreaticobiliary tract abnormality syndrome
The disease is a congenital disorder, there is no effective preventive measures, early detection and early diagnosis is the key to the prevention and treatment of this disease.
Complication
Complications of pancreaticobiliary confluence syndrome Complications, nosebleed, abdominal pain, intracranial hemorrhage
Often manifested as spontaneous bleeding, such as systemic blood stasis, hematoma, gastrointestinal bleeding, nosebleeds and joints, muscles, intracranial hemorrhage, some patients have frequent abdominal pain, increased pancreatic amylase in the blood and other symptoms of pancreatitis.
Symptom
Symptoms of pancreaticobiliary tract abnormal syndrome Common symptoms Biliary excretion blocked abdominal pain Bleeding bile duct rupture Blood gastrointestinal bleeding Bleeding intracranial hemorrhage
Due to obstruction of bile excretion, resulting in insufficient absorption of fat-soluble vitamin K, it can cause abnormal blood coagulation process. When there is serious lack of pipeline, it can often manifest as spontaneous bleeding, such as systemic blood stasis, hematoma, gastrointestinal bleeding, nosebleeds. As well as joints, muscles, intracranial hemorrhage, some patients have frequent abdominal pain, increased pancreatic amylase in the blood and other symptoms of pancreatitis.
Examine
Examination of pancreaticobiliary confluence syndrome
1. B-mode ultrasonography showed that the common bile duct area showed a constricted enlarged anechoic area, mostly spherical or elliptical, spindle-shaped, with clear wall and proximal end connected to the hepatic duct. The gallbladder was often pushed to the anterior wall of the abdomen. Combined with stone shadows.
2. X-ray angiography under the premise of normal liver function, physiological accumulation of angiography can show spherical or fusiform dilated common bile duct, PTC or ERCP can be directly injected into the biliary tract to show the dilated common bile duct.
3. CT examination showed that the dilated cyst and the normal gallbladder coexist.
4. MRI examination MRCP can show the common bile duct and the entire biliary system in a spherical or fusiform shape.
Diagnosis
Diagnosis and differentiation of pancreaticobiliary tract abnormal syndrome
According to clinical symptoms and signs, can be diagnosed, should be further CT examination, B-mode ultrasound to exclude hepatitis, cholangitis and other diseases.
With hepatitis, cholangitis is waiting for the disease to be identified.
