hemangiopericytoma
Introduction
Introduction to perivascular tumor Perivascular cell tumors (hemanyiopericytoma) are soft tissue tumors derived from pericytes and are rare. Because other soft tissue tumors also have a large number of blood vessels and a perivascular tumor-like appearance, it is often difficult to diagnose this disease. basic knowledge Sickness ratio: 0.0001% Susceptible people: no special people Mode of infection: non-infectious Complications: soft tissue tumors
Cause
The cause of perivascular tumor
(1) Causes of the disease
The cause is unknown.
(two) pathogenesis
The pathogenesis of soft tissue tumors derived from pericytes is not well understood.
Prevention
Perivascular cell tumor prevention
At present, there is no relevant content description. The main thing is to pay attention to the usual life and find timely treatment in time.
Complication
Perivascular cell tumor complications Complications, soft tissue tumors
Nodules, lung metastases, painless soft tissue masses of the fingers and toes.
Symptom
Perivascular cell tumor symptoms Common symptoms Fingers and toes are painless... Nodules and lungs are transferred to and around the blood vessel wall...
The tumor is a deep painless soft tissue mass, several centimeters in size, common parts are limb skin (rare), subcutaneous tissue and fascia, muscle, clinically similar lipoma can be invaded to the underlying tissue, except for subcutaneous tissue and muscle. Can also invade the epidural, paraspinal and pelvic retroperitoneal cavity, skin lesions are red, indurated large plaques or nodules, in general, limited to the skin, subcutaneous tissue small and superficial tumors have a better prognosis Large and deep tumors have a poor prognosis with a mortality rate of 50%, often due to lung metastasis.
Examine
Perivascular cell tumor examination
Histopathology: Tumors are characterized by densely accretive and dense pericytes surrounded by lumens and vascular buds of the endothelium. The nucleus is fusiform, and in some cases, vascular bifurcations such as antler-like, reticular fibers surround The endothelium of the capillaries, so in the stencil-stained sections, it can be seen that the tumor cells are confined around the reticular annulus around the endothelium, so reticular fiber staining often has considerable value for the diagnosis of the tumor, according to the organization. Characteristics, perivascular cells can be divided into benign, boundary and malignant, benign type does not metastasize, is obvious vascular type, mainly spindle-shaped pericytes, no nuclear fission, more limited than benign tumor cells The cells are relatively piled up, the change is not obvious, sometimes the mitosis is seen, the vascular lumen is often compressed, the outline is unclear, the degree of malignant tumor cell varies greatly, and the number of mitotic divisions varies, the immune group The staining of endothelial cells was negative, and the venom 1 and factor 8 related antigens were negative, and vimentin and laminin (1aminin) stained positively. Smooth muscle actin and scaven protein (desmin) staining were negative.
Diagnosis
Diagnosis and diagnosis of perivascular tumor
According to clinical manifestations, combined with histopathology can be diagnosed.
