Microspira infection
Introduction
Introduction to small spirulina infection The disease is an acute, recurrent and febrile disease caused by infection by rodents, and the original wound often heals quickly, but fever begins after 1 to 4 weeks (average 12 days). , chills, accompanied by systemic symptoms such as fatigue, and sometimes can affect the heart muscle, liver and kidney and die. Generally, it can heal itself after 4 to 8 weeks, but it can last for more than 1 year without treatment. basic knowledge The proportion of illness: 0.001% Susceptible people: no special people Mode of infection: non-infectious Complications: cardiomyopathy, hepatitis, nephritis
Cause
Cause of small spirulina infection
(1) Causes of the disease
After being bitten by a rodent, it is caused by a small spirulina infection.
(two) pathogenesis
After biting by a rodent, the original wound often heals quickly, but after 1 to 4 weeks (average 12 days), fever begins to appear, chills, accompanied by systemic symptoms such as fatigue, and pain, swelling and swelling of the skin at the original wound. Blue-gray nodules, which can be ruptured, surrounded by edema, with sacral lesions, with localized lymphangitis and lymphadenitis.
Prevention
Small spirulina infection prevention
First, rodents should be used. Laboratory workers should wear gloves. If they are bitten by rodents, they should be carefully cleaned and burned with silver nitrate or injected with a sufficient amount of penicillin.
Complication
Complications of small snail infection Complications, cardiomyopathy, nephritis
In some cases, the central nervous system may be involved, and sometimes the heart muscle, liver and kidney may be involved.
Symptom
Symptoms of small spirulina infection common symptoms urticaria rash coma wood zombie edema dysfunction wind group fatigue chills
After biting by a rodent, the original wound often heals quickly, but after 1 to 4 weeks (average 12 days), fever begins to appear, chills, accompanied by systemic symptoms such as fatigue, and pain, swelling and swelling of the skin at the original wound. Blue-gray nodules, it can be ulcerated, surrounded by edema, with sacral lesions, with local lymphangitis and lymphadenitis, fever can be as high as 40 ° C, after 2 to 4 days, body temperature retreat, after 3 to 7 days interval, It is also hot and has a large spotted rash, maculopapular rash or red wheal-like skin lesions, occasionally arthritis. In untreated cases, some patients may relapse, but the symptoms appear to be getting lighter and thinner at each episode. After several relapses of the rash, it is finally not developed. In some cases, the central nervous system may be involved. It may be coma, stupor, or even death. Sometimes it may also affect the heart muscle, liver and kidney, and it usually takes 4-8 weeks. Self-healing, but untreated can last for more than 1 year.
Examine
Examination of small spirulina infection
Blood routine examination, white blood cell count is normal or slightly higher, and eosinophil count is high, about 50% of syphilis serum test is false positive, exudate or local lymph node puncture extract is obtained from ulcer, dark field examination Spirochetes can be found. After being bitten by infected rats, their peripheral blood, enlarged lymph nodes and skin lesions can be seen by Giemsa staining or silver staining. Positive results can be obtained by guinea pig vaccination.
Histopathology: In the local inoculation site, the skin showed edema, and there was mononuclear cell infiltration and necrosis. Local lymph node proliferation. When the spirochete invaded the blood, the liver and renal tubules showed toxic bleeding and necrosis, and the myocardium, spleen and meninges were congested. Edema and turbid swelling.
Diagnosis
Diagnosis and identification of small spirulina infection
With a history of rat bites, combined with clinical symptoms, the disease is easier to diagnose. If necessary, a positive result can be confirmed by laboratory tests.
Need to be differentiated from periodic recurrent diseases such as malaria.
