Siberian rickettsial spotted fever
Introduction
Introduction to Siberian rickettsia spotted fever Siberian rickettsia spotted fever, also known as North Asiantick-bornerickettsiosis, North Asianticktyphus, is a type of spotted fever rickettsial disease. Siberian rickettsia is a natural epidemic disease caused by hard sputum transmission. The clinical features include fever, early sores, local lymphadenopathy and rash. basic knowledge The proportion of illness: 0.0005% Susceptible people: no specific population Mode of transmission: insect vector transmission complication:
Cause
Siberian rickettsia spotted fever
(1) Causes of the disease
Siberian rickettsia is a bacillus-like, multi-morphological form that accumulates in the nucleus of host cells and can be propagated in chicken embryo yolk sac and tissue culture. After inoculation of male guinea pigs, it can cause fever and scrotum swelling. The structure of the antigen is basically the same among different strains, and it is the same as other rickettsia parts in the spot heat group, and completely different from other rickettsia bodies outside the group.
(two) pathogenesis
When the disease bites the human body, the pathogen is injected into the human body, first in the local lymph nodes, and then released into the blood to form rickettsialosis, causing inflammation of the blood endothelial cells, causing abnormal function of various organs.
Prevention
Siberian rickettsia spotted fever prevention
The main purpose is to strengthen personal protection and avoid hard bites. When working in an infected area, you can wear protective clothing, apply repellents, or take small doses of broad-spectrum antibiotics as drug prevention. If necessary or necessary, chemical drugs can be used for livestock. , living room, human and animal must be sprayed through the plants on both sides of the way to kill.
1. Manage the source of infection
Deodorization treatment, focusing on specialized wards, bathing, changing clothes, spraying tiny amounts of insecticide into clothes and hair.
2, cut off the route of transmission
Strengthen health education, bathing, diligently changing clothes, clothing, being smashed, dry heat, damp heat, boiling, etc. can be used to kill cockroaches, 85 ° C for 30 minutes; ethylene oxide fumigation 6 ~ 24h to eliminate cockroaches.
3, protect susceptible people
Inactivate the vaccine and take temporary prevention with tetracycline or chloramphenicol.
Complication
Siberian rickettsia spotted fever complications Complication
Complications are rare.
Symptom
Siberian rickettsia spotted fever symptoms Common symptoms Muscle soreness Relaxation hot spot rash Red hare papules Hyperthermia Foreign Feather test Negative appetite deficiency Severe headache
The incubation period is 3 to 6 days. Most patients have prodromal symptoms such as headache, body aches, muscle aches and lack of appetite. The body temperature rises rapidly, and the disease is as high as 40 °C on the 3rd to 4th day. The fever is mostly in the form of relaxation and heat. Retreat, high fever lasts about 8 to 10 days, then gradually falls to normal. Most patients have early sores in the hard bite, which is characterized by a small infiltrating block. The upper part is covered with brown suede, surrounded by red halo, and multiple sores. Seen in the head, neck, shoulder or abdomen, often accompanied by local drainage of lymph nodes, on the 4th to 5th day after the onset of the disease, the patient has red elliptical maculopapular rash, varying in size, clear edges, fading, individual bleeding rash, Sometimes the rash can be extended to the palm of the hand, the soles and face, or only on the chest, back and the inside of the limbs. The whole course is accompanied by severe headache, low back pain and muscle pain, low blood pressure, conjunctival congestion, spleen can be touched, the prognosis of this disease Good, no recurrence, and rare complications.
Examine
Siberian rickettsia spotted fever check
Peripheral white blood cells are mostly normal or decreased, neutrophils are slightly increased, serological diagnosis is generally used for exo-fibe reaction, OX19 and OX2 are positive for complement fixation test, microagglutination test, indirect immunofluorescent antibody technology and enzyme-linked immunosorbent assay , have specific diagnostic value, pathogen isolation can be diagnosed.
X-ray chest radiographs showed no abnormalities.
Diagnosis
Siberian rickettsia spotted fever diagnosis
According to the disease area, history of bite, early sore, local lymphadenopathy and rash, it is not difficult to make a correct diagnosis, but still should pay attention to the identification of typhus, measles and epidemic cerebrospinal meningitis, serological diagnosis Generally, the external-Fei reaction, OX19 and OX2 are positive for complement binding test, microagglutination test, indirect immunofluorescent antibody technology and enzyme-linked immunosorbent assay, all have specific diagnostic value, pathogen separation can be diagnosed.
Should be noted with typhus, measles and epidemic cerebrospinal meningitis.
