Vulvar fibrosarcoma
Introduction
Introduction to vulvar fibrosarcoma Vulvar fibrosarcoma is a rare soft tissue sarcoma, a malignant tumor of fibroblasts that produces reticular fibers and collagen fibers. Slow growth, local invasive growth and recurrence can occur. Vulvar fibrosarcoma metastasis occurs in the late stage. basic knowledge The proportion of sickness: 0.012% - 0.023% Susceptible people: women Mode of infection: non-infectious Complications: vulvar hemangioma
Cause
Causes of vulvar fibrosarcoma
Causes:
The cause is not fully understood. Some scholars have reported that fibroid sarcoma was found in the original radiotherapy site 7 years after radiotherapy and chemotherapy in poorly differentiated vulvar squamous cell carcinoma.
Pathogenesis:
The tumor is round and lobulated, with a pseudo-envelope. The cut surface is grayish-white or gray-red, and the texture is tough. Most of them are accompanied by blood and necrosis. The microscopic examination is rich in fusiform fiber cells arranged in adult or "fishbone" structure. The cell morphology is relatively uniform, the cytoplasm is less, the boundary is unclear, the nucleus has a certain shape, and the mitotic figures are seen. Most of them have focal necrosis, and there are a number of collagen fibers and reticular fibers, according to the tumor cells. Polymorphism, number of mitotic divisions and pathological mitotic numbers were divided into well-differentiated and poorly differentiated types, immunohistochemical vimentin positive, S-100 and cytokeratin negative.
Prevention
Vulvar fibrosarcoma prevention
A) Develop good habits, stop smoking and limit alcohol. Eat some anti-cancer foods and alkaline foods with high alkalinity as appropriate to maintain a good mental state.
B) Have a good attitude to cope with stress, work and rest, not excessive fatigue.
C) Pay attention to the hygiene of the genital area and avoid long-term stimulation of secretions. Active treatment should be taken when genital itching occurs. Be careful not to use irritating drugs to clean the vulva.
D) Strengthen physical exercise, enhance physical fitness, and exercise more in the sun. Excessive sweating can excrete acidic substances in the body with sweat, avoiding the formation of acidic constitution.
E) If you have found nodules, ulcers and white lesions in the vulva, you should seek medical advice promptly.
Complication
Vulvar fibrosarcoma complications Complications vulvar hemangioma
Concomitant regional lymph node metastatic enlargement.
Symptom
Vulvar fibrosarcoma symptoms common symptoms shame mass
Occurs in the labia majora or clitoris, with or without painful masses, clear boundaries, varying hardness, fibrous tissue and low degree of malignancy, the quality is hard, otherwise the quality is soft, size (1.5 × 1.5) cm ~ (10 × 8)cm, the mass of the mass is small, and the adhesion is fixed after growing up. The local temperature of the mass can be higher, the surface can be seen with telangiectasia, and the lymph node metastasis can be accompanied by metastasis, and can be transferred to the lung through blood circulation, occasionally in the liver. And ribs, etc., local lymph node metastasis is rare, more malignant tumors are larger and softer, and progress more rapidly.
Examine
Examination of vulvar fibrosarcoma
Tumor marker examination, needle biopsy or needle biopsy.
Histopathological examination.
Diagnosis
Diagnosis and diagnosis of vulvar fibrosarcoma
Where the subcutaneous lumps of the vulva gradually increase, especially in the short-term, the soft tissue malignant tumor should be suspected. The diagnosis is based on pathological examination. For patients with infiltrated skin or skin ulcers, biopsy can be taken. If the skin is intact, For needle biopsy or needle biopsy, a biopsy or biopsy can also be performed.
There is no clear boundary between vulvar fibrosarcoma and dermatofibrosarcoma sarcoma, so attention should be paid to differential diagnosis.
