Vulvar papilloma
Introduction
Introduction to vulvar papilloma Vulvar papilloma is a tumor of epithelial origin. The lesions occur mostly in the labia majora. They can also be seen in the genital area, the clitoris and the anus. The vulvar papilloma is divided into two types, namely papilloma and papillary tumor. There is more than one type of fibrous papilloma with cutaneous hyperplasia, which can be regarded as a subtype of vulvar papilloma. The vulvar fibrous papilloma is between the vulvar papilloma and the soft fibroid, which constitutes a moderate amount of tumor epithelium and fibrous tissue. The fibrous connective tissue is often more than the epithelium, so the texture is soft and tough. Sometimes most of the clinical findings are not true papilloma, but only nipple formation. True papilloma is a benign epithelial tumor. basic knowledge The proportion of illness: 0.002% Susceptible people: women Mode of infection: non-infectious Complications: vaginitis
Cause
Cause of vulvar papilloma
Causes:
Vulvar papilloma is a papillary mass that is caused by local inflammatory stimulation of the vulva skin or mucous membrane, and the surface is outwardly grown. It is a lesion with epithelial hyperplasia.
Pathogenesis:
1. Typical papilloma: The local eye is seen as single or multiple local protrusions. The epithelial hyperplasia is dominant. There are numerous papillary protrusions on the surface of the tumor. The nipple is small and many, the quality is slightly hard, and the stratified scale can be seen under the microscope. The epithelium has obvious hypertrophy of acanthosis cells, and the epithelium protrudes to the surface to form a majority of papillary morphology. The epithelial foot becomes thicker and extends into the dermal fibrous connective tissue. The epithelial cells are arranged neatly, and the cells have no obvious variability, but occasionally visible. A small number of mitotic figures, the tumor malignant rate is low, 2.5% to 3%.
2. Papillary papilloma: The nipple is fine and dense, such as cauliflower or scorpion, and the texture is hard. Under the microscope, the epithelial acanthosis cells are hypertrophied, the basement membrane is flat, and there is no obvious epithelial foot extending downward.
3. Fibrous epithelial papilloma: Fibrous epithelial papilloma is composed of tumor epithelium and fibrous tissue. It belongs to papilloma with more epithelial components than fibrous tissue. The surface of the tumor has wide and thick protrusions or folds. The surface is covered with stratified squamous epithelium, the cells have moderate hyperplasia, the cells have no abnormality, and the epithelial feet are large and wide, and the tumor generally does not undergo malignant transformation.
Prevention
Vulvar papilloma prevention
Regular physical examination, early detection, early treatment, and good follow-up. Self-examination of vulva to prevent vulvar papilloma:
First, you can use a small mirror, placed under the vulva, moving the mirror back and forth, and looking at your genital area with the help of a mirror. In addition, by observing vaginal secretions, such as vaginal discharge and menstrual blood color, turbid, thick, can also find some clues. The normal leucorrhea is a thin liquid with an innocent color. Normal menstrual blood is bright red or light red, and some people will have a little blood clot.
Second, the smell is to sniff the secretions, menstrual blood or the smell of the vulva. The usual normal odor is a light astringent, sweaty or tasteless. If there is a stench, rancid smell or a special smell, problems may occur.
Third, touch the first hand to clean, use the index finger and the middle finger of the two fingers of the "finger belly" (commonly known as "finger belly"), starting from the "yin" part, from top to bottom, in order to touch the vulva until the anus. When you touch the vulva normally, the feeling should be smooth and soft. If you don't press hard, you won't feel pain. Of course, you shouldn't feel small nodules or bumps under normal circumstances. On the contrary, it may be sick.
Complication
Vulvar papilloma complications Complications vaginitis
Because the part is prone to friction, it often causes blood and vulva, vaginal infection.
Symptom
Vulvar papilloma symptoms Common symptoms Itching vulvar ulcer pubic mass
Vulvar papilloma often occurs in elderly women. The age of onset is mostly 40 to 70 years old. The disease grows slowly and can be asymptomatic, but it can also have a history of genital itching and local inflammation. The lesion is more common in the labia majora, haze, clitoris or anus. Surroundings, etc., can be single or multiple, the lesions are generally small, occasionally as large as 4 ~ 5cm, the tumor can be pedicled grape-like or cauliflower-like, such as large tumors, due to repeated friction, the surface can be broken, bleeding and Infection, gynecological examination revealed a nipple-like mass in the vulva, which can be single or multiple, and the quality is slightly hard.
Examine
Examination of vulvar papilloma
1. Secretion smear examination: The smear of the secretion is examined by microbiological examination, and the cervical smear is used as a segmental diagnosis if necessary to exclude genital malignant tumors.
2. Tumor marker examination.
Live tissue was pathologically examined.
Diagnosis
Diagnosis and diagnosis of vulvar papilloma
diagnosis
Diagnosis of vulvar papilloma is generally not difficult. According to clinical manifestations, a preliminary diagnosis can be made. The diagnosis should be based on the pathological results after biopsy.
Differential diagnosis
Typical papilloma and condyloma acuminata are sometimes difficult to distinguish clinically, and should be differentiated from vulvar flattened genital warts and early vulvar cancer.
1. Vulvar condyloma: Most cases occur in the vulva and perianal, with multifocal papillary hyperplasia, a history of infection, positive for human papillomavirus, rapid development, microscopic thickening of the epithelial layer of cells, visible hollow cells.
2. Vulva flattened wet warts: papules or nodules, mostly in the labia and perineum, easy to rupture, secretions can be found in Treponema pallidum, syphilis seropositive.
3. Vulvar cancer: papillary or cauliflower-like hyperplasia, pain, itching symptoms, easy to form ulcers, rapid growth, pathological examination can be diagnosed, the vast majority of squamous cell carcinoma.
4. Vulvar fibroids: polypoid, under the microscope, there are obvious components of fibrovascular interstitial.
