Vulvar syringoma
Introduction
Introduction to vulvar sweat duct tumor Vulvar syringoma is a benign tumor that differentiates into a small sweat gland duct in the epidermis. basic knowledge The proportion of illness: 0.005% Susceptible people: women Mode of infection: non-infectious complication:
Cause
The cause of vulvar sweat duct tumor
(1) Causes of the disease
A considerable number of patients have a family history of genetic factors, indicating that some of the morbidity is related to hereditary factors. Three of the families have reported sero-tumor tumors, or there are other sputum-like tumors in the family (such as hair epithelioma, sebaceous gland adenoma). Etc.), diffuse familial syringoma is autosomal dominant, because the disease occurs in women, and adolescence is aggravated, gestation, premenstrual or the use of female hormones when the rash increases, suggesting that vulvar syringoma and Related to endocrine disorders.
(two) pathogenesis
The tumor is located in the superficial dermis, in the dermis, and the upper part of the basophilic epithelial cells is aggregated with solid cell cords or cystic dilatation and ducts embedded in the fibrous matrix. The duct wall is usually lined with two rows of epithelial cells. In most cases, the outer layer of cells is flat, the cytoplasm is reddish, the nucleus is small, the lumen is filled with homogeneous eosin and fine granular degeneration, the inner cells are secreted, and the cells can be solid. , or one end is a solid strip, the other end is a duct-like shape, shaped like a comma or a braid, which is quite characteristic.
Prevention
Vulvar sinus tumor prevention
1. Use female hormones with caution. If abnormal skin lesions should be diagnosed and treated early, follow up well.
2, pay attention to keep the genital area clean and dry, if there is abnormal secretion, due to the attention, go to the hospital to do the corresponding inspection.
3, pay attention to nutrition, enhance physical fitness. Eat more foods rich in vitamins and protein, pay attention to work and rest, exercise more, rest more.
4, regular physical examination, pay attention to wound protection, to prevent the occurrence of infection.
Complication
Vulvar bronchial tumor complications Complication
Local skin infections.
Symptom
Vulvar syringe symptoms common symptoms pruritus sensation vulvar skin swelling papular nodules
Vulvar sinus tumors generally have no symptoms. In summer, some skin lesions have mild swelling, conscious pruritus, and the skin lesions often increase gradually. When they reach a certain size, they no longer grow up, but rarely self-resolved, no self-healing tendency, and the course of disease. Slow, can last for decades, the main part of the female vaginal canal tumor is the labia majora, pubic lice, perineum, a few can be seen in the labia minora and clitoris, skin lesions are skin color, pale red, light brown papules or nodules, needle tip To small soybeans, the surface is smooth, with a waxy luster, small papules with a diameter of 1 to 2 mm. The nodules are often larger than other parts of the sac tube, which can be fused into plaques, ranging from several to several hundred. Or cluster distribution, the rash is affected by the menstrual cycle and can be increased before menstruation.
Examine
Examination of vulvar sweat duct tumor
Hormone level monitoring, tumor marker examination.
Histopathological examination.
Diagnosis
Diagnosis and diagnosis of vulvar sweat canal tumor
diagnosis
According to the age, location and clinical features of the disease, histopathology can make a diagnosis.
Differential diagnosis
Need to be identified with the following diseases:
1.FOX-Fordyoe disease, also known as apocrine miliary rash, occurs in adolescent or post-puberty women, the site of the disease in the armpits, areola, pubic bone, the labia majora and the perineum and other apocrine glands, distributed symmetrically, the rash is Skin color, light brown solid hair follicles, no fusion, some papules have hair follicles at the top, can squeeze a small amount of turbid secretions, the affected area is sparse or shedding, consciously paroxysmal itching, pathological examination shows hair follicle wall Sponge edema blister, hair follicles leaking head acanthosis, inflammatory cells infiltration in the dermis around the head.
2. Bowen-like papulosis is more common in young women. Skin lesions occur in the groin, labia majora and perianal. The typical lesions are multiple brown-black flat papules. The boundary is clear. The surface of the papules is bright and velvety-like, scattered or The group integrates linear or circular, generally no symptoms, and the pathological changes are low-grade malignant squamous cell carcinoma.
3. Sebaceous gland ectopic disease occurs in the mucosa, mainly in the oral mucosa, also in the genital mucosa such as the labia minora. It is a round or slightly large round, white or yellowish papule, clustered or evacuated, not fused. Clear borders, no symptoms, each pimples consists of mature sebaceous gland lobes, directly open to the mucosal surface, no hair follicles.
4. Sclerosing basal cell carcinoma Tumor tissue consists of basal-like cells, often arranged in narrow and narrow strips, and the surrounding connective tissue proliferates significantly, which can be differentiated from sweat duct tumors.
