isolated pulmonary eosinophilic infiltrates
Introduction
Introduction to simple pulmonary eosinophilic infiltration Simple pulmonary eosinophilic infiltration, also known as Lvf's syndrome, was first described by Ruffin in 1932. Simple pulmonary eosinophilic infiltration is characterized by migratory pulmonary infiltration with elevated peripheral blood eosinophil count, mild pulmonary symptoms, most of which only have mild cough, and the course of disease is self-limiting, often 3 to 4 weeks. Healed by himself. basic knowledge The proportion of illness: 0.005%-0.008% Susceptible people: no specific people Mode of infection: non-infectious Complications: urticaria biliary ascariasis
Cause
Causes of simple pulmonary eosinophilic infiltration
Aphid infection in parasites (20%):
Experiments have shown that after eating aphid eggs, the larvae migrate to the lungs and the typical lung manifestations and eosinophils can occur. Other parasites causing this disease include hookworms, filars, aphids, ginger worms, trichinella, and amoeba.
Drug reaction (25%):
The drug has alveolar acid caused by salicylic acid, aspirin, penicillin, nitrofurantoin, phenylbutazone, chlorpropamide, hydralazine, mecamylamine, sulfa drugs and methotrexate. Hypersensitivity.
Inhalation of pollen (10%):
The disease is seasonally prevalent in some areas, so it is speculated that environmental antigen factors are also a possible cause in some areas. Sometimes the disease can also occur by inhaling pollen.
Pathological changes are mainly located in the interstitial lung, alveolar wall and terminal bronchiole wall, with irregular eosinophil infiltration, and sometimes a cluster of eosinophils can be seen in the alveoli, rarely involving blood vessels.
Prevention
Simple pulmonary eosinophilic infiltration prevention
Pay attention to food hygiene and prevent infection with aphids, hookworms, silkworms, mites, ginger worms, trichinella and amoeba.
Complication
Complications of simple pulmonary eosinophilic infiltration Complications urticaria biliary ascariasis
The disease can be caused by ticks, biliary ascariasis, and because of hookworms, there may be dermatitis and heterosexuality.
Symptom
Symptoms of simple pulmonary eosinophilic infiltration common symptoms fatigue chest tightness hernia chest tightness hemoptysis with fever eosinophilia pharyngeal foreign body sensation
The disease can be asymptomatic, only found in X-ray examination, most patients have mild cough, a small amount of sticky, may have fatigue, headache, anorexia, low fever and chest tightness, etc., similar to a cold, X-ray performance is often density The faint, unclear flaky shadows are distributed in the unilateral or bilateral lungs. They are short-lived, mostly disappearing in 1-2 weeks, and can appear in other parts, most of which are less than one month.
Examine
Examination of simple pulmonary eosinophilic infiltration
X-rays are often characterized by lighter-density, smeared shadows with unclear borders, distributed in unilateral or bilateral lungs, with short-term migration, mostly disappearing in 1-2 weeks, and appearing in other parts, most of the time Not more than 1 month.
Peripheral white blood cells can be normal or slightly increased, eosinophils are significantly increased, up to 10% to 20%, or 1000 to 2500/mm3, and more eosinophils can be seen in the sputum.
Diagnosis
Diagnosis and differentiation of simple pulmonary eosinophilic infiltration
The diagnosis of this disease is mainly based on the increase of peripheral blood eosinophils with migratory pulmonary infiltration, and the clinical symptoms are mild, self-healing characteristics, etc., suspected to be caused by aphid infection, after the symptoms appear 2 months, that is, the cercaria After the body develops into an worm, it is used for fecal collection.
Simple pulmonary eosinophilic infiltration should be differentiated from asthmatic pulmonary eosinophilic infiltration, tropical pulmonary eosinophilic infiltration, persistent pulmonary eosinophilic infiltration, and invasive pulmonary tuberculosis.
