post-inflammatory melanosis
Introduction
Introduction to melanosis after inflammation Postinflammatory melanosis is a skin pigmentation that occurs after an acute or chronic inflammatory process of the skin. basic knowledge The proportion of sickness: 0.2% Susceptible people: no special people Mode of infection: non-infectious Complications: herpes
Cause
Causes of melanosis after inflammation
(1) Causes of the disease
Pigmentation is a common phenomenon after skin inflammation. In many facial melanosis, pigmentation often involves many factors, and is often associated with the presence of photosensitizers and photosensitivity contact dermatitis caused by exposure, in some inflammations. Sexual stimuli such as physical (trauma, friction, heat, various radiation), chemical (drugs, primary irritants, allergic sensitive substances, photosensitizers), infectious agents, nutritional disorders, etc., can also cause pigments calm.
(two) pathogenesis
The pathogenesis of this disease is not fully understood. Histological examination in many inflammatory skin diseases shows an increase in melanocyte activity, which is likely due to the reduction or partial removal of sulfhydryl groups in the skin due to inflammatory reactions. Enzyme activity is increased to cause hyperpigmentation. Whether skin hyperplasia after skin inflammation is not determined by the degree of inflammation but is determined by the nature of skin diseases. Some skin diseases such as lichen planus, pityriasis rosea, herpes zoster, lupus erythematosus, Fixed drug eruption, herpes-like dermatitis, subarachnoid pustulosis, neurodermatitis, insect bite dermatitis, second stage syphilis, mast cell disease, pyoderma, etc., easily cause different degrees of skin pigmentation, the degree and inflammation The duration and intensity of the disease are particularly pronounced in dark-skinned people and those who are easy to tan, while pigmentation often worsens or hypopigmentation after other skin diseases. Studies of these differences will help to further elucidate melanin. The relationship between cells and epidermal cells, in addition, the duration of pigmentation varies, usually weeks or months after inflammation, color The stagnation can gradually subside, but the inflammatory process at the junction of some primary cells or epidermal dermis, such as lichen planus, discoid lupus erythematosus, fixed drug eruption, etc., can cause melanin to accumulate in the upper part of the dermis and accumulate in melanin. Intracellular and extracellular (pigment incontinence), the resulting pigmentation is often very long-lasting.
Prevention
Prevention of melanosis after inflammation
Pay more attention to living habits and find timely treatment in time.
Complication
Complications of melanosis after inflammation Complications herpes
Spotted, pigmented, pigmented, herpes.
Symptom
Symptoms of melanosis after inflammation Common symptoms Benign reactivity changes skin pigmentation deepens
Pigmentation occurs faster after dermatitis. After detachment, the inflammatory phenomenon disappears quickly, and the pigment also fades faster. The pigmentation spots are light brown, purple to dark black, and are confined to the skin inflammation area. When the erythema subsides, it often It usually takes several months to gradually fade away. After sun exposure or re-inflammation, the pigment is further deepened, even mildly lichenified, sometimes lasting for several years. In the dark-skinned race, the regression is particularly slow, generally without subjectivity. It is common to have diffuse pigmentation left after contact with asphalt, tar, etc., which is caused by phototoxic dermatitis, and is accompanied by suppurative oily acne (oily rash).
Depending on the type and distribution of pigmentation, it sometimes helps to trace the original skin diseases such as lichen planus, herpes zoster, herpetic dermatitis and papular urticaria. Fire erythema often occurs after long-term local exposure to fire and heat. Capillary vasodilation, followed by reticular pigmentation, after some moss-like drug eruptions, pigmentation is very obvious, showing a characteristic lipomelanic reticulosis.
Examine
Examination of melanosis after inflammation
Erythrocyte sedimentation rate (ESR), eosinophil count, skin smear, microscopy, urine routine, blood routine, routine.
Diagnosis
Diagnosis and differentiation of melanosis after inflammation
According to the pigmentation caused by the original skin inflammation (skin disease or skin inflammation stimulation), it is easy to make a diagnosis, but sometimes some skin inflammation damage or inflammatory irritation is often light, not noticed by the patient or the skin lesion is only temporary Sexuality, clinically difficult to detect, often can not be traced back to the cause.
