Vulvar yolk sac tumor
Introduction
Introduction to vulvar yolk sac tumor Vulvar yolk sac tumor is a tumor with high malignancy of germ cells in the ovary. It has a hard, active painless mass in the vulva. The size of the tumor is different. Some are only swollen vulva; ulcers or cellulitis on the surface It is tender. basic knowledge Probability ratio: 0.001% probability of adolescent women Susceptible people: women Mode of infection: non-infectious complication:
Cause
Vulvar yolk sac tumor cause
(1) Causes of the disease
The yolk sac tumor of the vulva is due to the lack of embryonic tissue conductors during the determined phase of germ cell migration. As a result, the germ cells are misplaced, and some of them stay abnormally under the skin of the pubic or labia.
(two) pathogenesis
The tumor is a brown or gray-white mass with a pseudo-envelope, a capsular sac, and both, mostly honeycomb microcapsules and small sacs, filled with water-like liquid, bloody serum, viscous liquid, and solid tissue With bleeding and necrosis.
Microscopic examination showed a lumen composed of mutual communication. The cavity surface was lined with endothelial cells. The cells were separated by irregular fibers and nested. Many cytoplasmic and extracellular anti-amylase PAS-positive transparent bodies and blood vessels were observed. The SD (Schiller-Duval) body characteristic of the tumor-forming crown of radioactive tumor cells is the main basis for diagnosis.
Tumor tissue AFP can be positively expressed and partially CEA positive.
Prevention
Vulvar yolk sac tumor prevention
Pay attention to regular physical examination, find out as soon as possible, treat in time, and follow up well.
Complication
Vulvar yolk sac tumor complications Complication
Vulvar yolk sac tumors are associated with ulceration after ulceration.
Symptom
Vulvar yolk sac tumor symptoms Common symptoms Skin tenderness pubic mass swell swelling
Short course of disease, generally 1 ~ 9m, rapid development, mostly occurs in the labia majora, can also be seen in the clitoris, manifested as painless, hard, active mass, can also only show swelling of the vulva, tenderness, surface skin can be There is an ulcer or cellulitis-like change, and the size of the tumor is (1.2 × 1.5) cm ~ (10 × 6) cm.
Examine
Examination of vulvar yolk sac tumor
Fetoprotein globulin (AFP), carcinoembryonic antigen (CEA), secretion examination.
Histopathological examination.
Diagnosis
Diagnosis and diagnosis of vulvar yolk sac tumor
Because vulvar yolk sac tumors are rare, the first step is to exclude ovarian yolk sac tumor metastasis to the vulva. Alpha-fetoprotein (AFP) is a specific marker for ovarian yolk sac tumors, but not all vulvar yolk sac tumor patients have serum. AFP is elevated, especially for patients with low serum AFP, it should be distinguished from other diseases, pathological examination has a clear diagnostic effect.
Identification by pathological examination with other malignant tumors of the vulva.
