water pain
Introduction
Introduction to water pain Hydropathy is a skin reaction induced by water. It has a strong burning sensation after bathing, but no visible skin damage lasts for 15 to 45 minutes. It may be due to a demethylation that occurs after contact with water. Adrenal gland pain. The disease can be considered as an extension of the aquagenic pruritus phenomenon. basic knowledge Sickness ratio: 0.001%-0.005% Susceptible people: no special people Mode of infection: non-infectious Complications: patellofemoral joint pain
Cause
Cause of hydropathic pain
(1) Causes of the disease
Hydropathic pain is a skin reaction induced by water. The pathogenesis of pain involves sympathetic nerves that mediate pain sensation. Studying reflex sympathetic dystrophy shows that sympathetic intervention can eliminate pain and hyperalgesia, local injection or injection in burning. Applying methyl epinephrine can cause severe pain. Local topical clonidine (Clonidine)-2 adrenal gland can antagonize, can eliminate burning nerve pain caused by mechanical or cold, hyperalgesia, some of this hydropathic pain Patients can be treated with propranolol or clonidine, so the disease may be demethyl adrenergic pain, propranolol is a beta adrenergic blocker, it is more than a2 adrenal blocker cola The effect is poor, the duration of pain is the same as the time when the noradrenal granules released from the nerve endings are exhausted. The aqueous itching may have the same demethylating adrenal gland, because it can be successfully treated with clonidine, so the water pain The disease is also considered a special type of watery itching.
(two) pathogenesis
The pathogenesis is still not clear. The pathogenesis of pain involves sympathetic nerves that mediate pain sensation. Studies of reflex sympathetic dystrophy indicate that sympathetic intervention can eliminate pain and hyperalgesia, local injection or over-application of norepinephrine in burning. It can cause severe pain. Topical topical clonidine (Clonidine)-a2 adrenergic antagonist can eliminate burning nerve pain caused by mechanical or cold, hyperalgesia. Some patients with this type of hydropnea can use propranolol. (Centre) or clonidine treatment, so the disease may be demethyl adrenergic pain.
Prevention
Hydropathic disease prevention
There is no effective preventive measure for this disease, and avoiding contact with water is an effective way.
Complication
Hydropathic complications Complications, patellofemoral joint pain
No other complications were seen.
Symptom
Symptoms of water pain, common symptoms, skin pain, persistent pain, persistent fever
After bathing, there is a strong burning sensation in the body, but no visible skin damage, lasting 15 ~ 45min, topical topical clonidine (Clonidine) - 2 adrenergic antagonist, can be eliminated, and can be repeated, can be diagnosed.
Examine
Hydropathic examination
According to reports in the literature, plasma catecholamine levels are elevated in skin pain, with phenyl phenylephrine at 726 ng/L (plasma) before bath and 1103 ng/L after bath (normally 120-180 ng/L), adrenaline. 120ng/L before bath, 163ng/L after bath (normally less than 60ng/L), 854ng/L before total catecholamine bath, 1266ng/L after bath (normal 140730ng/L), blood count, blood biochemical index The urine test was normal, and IgA, IgG, C3, albumin and fibrinogen were normal.
Skin biopsy is normal, and the mast cell count is also normal.
Diagnosis
Diagnosis and diagnosis of water pain
According to clinical manifestations, it is not difficult to diagnose.
