Orbital ossifying fibroma

Introduction

Introduction to orbital ossifying fibroma Osteosynthesis (ossifyingfibroma) is an acquired fibrous osteoma that often affects the tibia. It occurs in the craniofacial bone and occurs in the skull, mostly in the frontal bone, ethmoid and sphenoid bone, and also in the humerus. The bone is the most common in the jaw, and the eyelids are often involved. The histopathological feature is that the lamellae are surrounded by bone and osteoblasts in the fibrous tissue matrix, and osteoblasts are visible. Because it occurs in young people, it is also known as young ossifying fibroma. basic knowledge The proportion of illness: 0.03% Susceptible people: no special people Mode of infection: non-infectious Complications: eyeballs

Cause

Causes of orbital ossifying fibroma

Osteofibroma is a congenital dysplasia composed of fibrous and bone-like substances that occur almost exclusively in the tibia and sometimes in the tibia. This disease often involves anterior humerus, and its course of disease is the course of a hamartoma. The disease is a tumor that is different from the fibrous structure. The exact cause is unknown. It grows slowly, is asymptomatic at an early stage, grows faster during puberty, and is more stable afterwards. Occurs in the maxilla, which can affect the maxillary sinus, the iliac crest and the tibia.

Prevention

Orbital ossifying fibroma prevention

(1) Minimize infection and avoid exposure to radiation and other toxic substances, especially drugs that inhibit immune function; active virus and certain physical properties (such as radiation), chemical (such as anti-epileptic drugs, adrenal gland) Long-term application of corticosteroids. Pay attention to personal and environmental hygiene, avoid drug abuse, and pay attention to personal protection when working in a harmful environment.

(2) Appropriate exercise, enhance physical fitness, and improve their disease resistance.

Complication

Ocular ossifying fibroma complications Complications

Nasal lacrimal duct obstruction, tear overflow, eyeball protrusion, eyeball displacement, craniofacial deformity, visual impairment.

Symptom

Symptoms of orbital ossification of fibroids Common symptoms Eyelid swelling and pale green visual impairment Eyeball prominent tears eyeball shift nasolacrimal duct obstruction craniofacial bone deformity

Osteofibroma usually occurs in adolescents, showing painless progressive ocular protrusion, and may have abnormal appearance of craniofacial bone. The direction of eyeball displacement depends on the lesion, and the tumor in the frontal bone shifts the eyeball downward. The maxillary bone is displaced upwards. In addition, due to the different primary position of the lesion, the clinical symptoms are different. The sphenoid sinus or posterior ethmoid sinus lesions have vision loss due to oppression of the optic nerve; tear bone and ethmoid lesions may be blocked due to nasolacrimal duct And tears overflow; involving the third, IV, VI, V for the brain nerve can appear corresponding symptoms.

Examine

Examination of orbital ossifying fibroma

Pathological examination: gross pathological examination showed that the ossifying fibroma had no cystic membrane, which was tough. Under light microscope, the trabecular bone was evenly distributed in the fibrous interstitial, surrounded by osteoblasts and a number of osteoclasts, bones. The trabecular bones are irregularly arranged. These trabecular bones are considered to be a fibrous connective tissue matrix. The presence of osteoblasts helps to differentiate ossifying fibroids from bone fiber dysplasia, the latter being immature. Without the bone composition of osteoblasts, ossifying fibroma is considered to be a true bony tumor, and bone dysplasia is considered to be a retention at the developmental stage of the osteogenic stage.

Imaging examination: X-ray and CT scan are the best methods for diagnosing ossifying fibroma, such as other fibrous bone lesions. The characteristics of ossifying fibroma are round or elliptical, with clear boundaries and local enlargement of affected bone. In the soft tissue area, the lesion often shows a homogeneous mass, but in the bone matrix, there is a focal transparent area due to bone spurs.

Diagnosis

Diagnosis and differentiation of orbital ossifying fibroma

In clinical and histopathology, the differential diagnosis of young ossifying fibroma includes: bone dysplasia and all other fibrous bone lesions, most recent authors believe that the diagnosis of bone dysplasia and ossifying fibroma The proof is correct. It is easy to find the lesion according to the X-ray film and CT scan results, but the qualitative diagnosis often depends on histopathological examination.

Abnormal hyperosteogeny: X-ray shows unclear boundary, no focal transparent area, pathological examination can be identified.

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