Chloral hydrate poisoning

Introduction

Introduction to chloral hydrate poisoning Chloral hydrate (ch1oralhydrate) is a commonly used sedative and antispasmodic drug. Oral or enema. Excessive single dose or repeated use in a short period of time can cause acute poisoning. Mother poisoning can cause fetal or milk poisoning. After the absorption of the poisoning amount, it can inhibit the functions of the central nervous system, the vascular movement center and the heart and damage the liver and kidney. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific population Mode of infection: non-infectious Complications: proteinuria, hematuria

Cause

Causes of chloral hydrate poisoning

Poisoning is often caused by overuse or repeated medications in the short term.

Prevention

Hydrated chloral poisoning prevention

Ethanol and monoamine oxidase inhibitors can increase the toxic side effects of chloral hydrate. It is best not to use them at the same time. If they are used at the same time, they should be appropriately reduced.

Complication

Hydrated chloral poisoning complications Complications, proteinuria, hematuria

Slow disease may cause jaundice due to liver and kidney damage, hepatomegaly, liver tenderness, elevated transaminase, proteinuria and hematuria.

Symptom

Symptoms of chloral hydrate poisoning common symptoms diarrhea hepatomegaly nausea gastrointestinal bleeding

The main signs of acute poisoning are drowsiness and even coma, weak pulse, decreased blood pressure and body temperature, weak breathing, slow, or irregular rhythm, slow heartbeat and other abnormal heart rhythms, purpura or pale, dilated pupils (later enlargement), weakened light reflex Or disappear, muscle relaxation, reflexes disappeared, etc. Some patients develop pulmonary edema and cerebral edema, which may eventually lead to respiratory or circulatory failure. After taking a large amount of chloral hydrate, severe gastrointestinal irritation or corrosion may occur, and the throat and the throat may appear. Esophageal pain, nausea, vomiting, abdominal pain, diarrhea, or gastrointestinal bleeding, hematuria, proteinuria, hepatomegaly, jaundice, etc., a small number of sick children with paralysis, mental confusion and epileptic seizures.

Examine

Examination of chloral hydrate poisoning

The chlorate concentration can be determined by vomit, liquid, urine, and blood test.

Diagnosis

Diagnosis and identification of chloral hydrate poisoning

diagnosis

Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.

Differential diagnosis

It is differentiated from other types of sedative drug poisoning, for example, with barbiturate poisoning, anxiolytic drug poisoning, and bromide poisoning.

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