Insecticide poisoning

Introduction

Introduction to insecticide poisoning The commonly used organic nitrogen pesticides are insecticidal mites, which are high-efficiency broad-spectrum organic nitrogen agricultural insecticides and acaricides, and are effective against insects resistant to organophosphorus, organochlorine and carbamate insecticides. Insecticidal mites have low solubility in water, are relatively stable in strong acids, and rapidly hydrolyze in weak acid and weak base solutions. Poisoning can occur if you accidentally take this type of pesticide, skin contact or inhalation of its droplets. basic knowledge The proportion of illness: 0.035% Susceptible people: no specific population Mode of infection: non-infectious Complications: hemorrhagic cystitis

Cause

Insecticide poisoning cause

Poisoning can occur if you accidentally take this type of pesticide, skin contact or inhalation of its droplets. Acute insecticidal poisoning is mainly caused by the sprayer not wearing protective clothing, masks, sprinklers and insecticides. The protective gloves of the finished packaging workers are leaking and there are a lot of insecticides, contaminated skin and inhaled by the respiratory tract. When taking or taking 25% of the insecticidal sputum solution, it can be acutely poisoned.

The mechanism of poisoning of insecticides is complicated. The main mechanism may be direct anesthesia and cardiovascular inhibition. The aniline active groups of insecticidal and its metabolites can cause methemoglobinemia and hemorrhagic cystitis. Insects inhibit serum monoamine oxidase and other enzymes, leading to intricate clinical manifestations.

Prevention

Insecticide poisoning prevention

prevent disease

1. Improve the packaging machine and workers of the insecticidal cockroach liquid, and apply the labor protection products to avoid swaying leakage and skin pollution.

2, medical staff should be alert to insecticides and other pesticides, especially organophosphate insecticides mixed poisoning, while missing or misdiagnosed, lost the opportunity to rescue.

safety warning

1. Avoid in the process of production, packaging, storage, transportation, use, due to accident or protection inadvertently, in violation of the operating procedures, misuse, the poisoned person caused poisoning through the digestive tract.

2, oral poisoning application of vomiting, gastric lavage (with 1% ~ 2% sodium bicarbonate solution), catharsis, fluid replacement, diuretic and other methods to promote the discharge of poison; purple sputum can be used in the blue, glucose and vitamin C intravenous; hematuria Adrenal cortex hormones are available.

3, skin contact or inhalation poisoning, immediately out of contact with the environment, and wash the contaminated parts with soapy water, the symptoms of poisoning after absorption refer to oral poisoning treatment.

Complication

Insecticide poisoning complications Complications hemorrhagic cystitis

Direct anesthesia and cardiovascular inhibition, aniline active groups of insecticidal and its metabolites can cause methemoglobinemia and hemorrhagic cystitis, and insecticidal mites inhibit serum monoamine oxidase and other enzymes, leading to intricate clinical which performed.

Symptom

Symptoms of insecticidal cockroaches poisoning common symptoms fatigue, lethargy, limbs, cold heartbeat, urinary urgency, frequent urinary protein, urinary nausea and pain

Acute poisoning is mild, vomiting, dizziness, fatigue, lethargy, sweating, bradycardia, cold limbs, and prominent sleepiness, severe coma, reflexes, and even death from respiratory and circulatory failure Poisoning patients often have frequent urination, urgency, dysuria, hematuria, proteinuria and purpura, skin contact poisoning and burning, hemp, itching, local miliary papules, so sleepiness, purpura, hemorrhagic cystitis The major syndrome is the main feature of severe poisoning.

Examine

Insecticide poisoning check

Red blood cells, protein, a small amount of white blood cells and casts appeared in the urine, serum ALT increased in a small number of patients, and the urinary insecticidal mites and their metabolite 4-chloro-o-toluidine increased (the normal value was 0.02±0.025 mg/L, among which Insecticide was 0.01±0.023mg/L, 4-chloro-o-toluidine was 0.010±0.16mg/L), blood methemoglobin increased, serum monoamine oxidase decreased in severe poisoning, and arrhythmia and myocardial damage appeared in ECG.

Diagnosis

Diagnosis and identification of insecticidal cockroach poisoning

diagnosis

Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.

Differential diagnosis

Mild poisoning

Dizziness, headache, fatigue, chest tightness, nausea, lethargy and other symptoms, blood methemoglobin accounted for 30% of total hemoglobin; or chemical cystitis, with microscopic hematuria; or mild toxic heart disease, such as I degree atrioventricular block, mild ST-T changes, frequent premature beats.

2. Moderate poisoning

a) shallow coma;

b) methemoglobin accounts for 30-50% of the total hemoglobin;

c) moderately toxic heart disease, such as atrial fibrillation or flutter, second degree atrioventricular block, myocardial damage, etc.;

d) chemical cystitis, frequent urination, urgency, symptoms of dysuria, with hematuria.

3. Severe poisoning

In addition to the above symptoms, one of the following conditions:

a) coma;

b) blood methemoglobin exceeds 50% of total hemoglobin;

c) sustained heart rate slowdown, hypotension, shock;

d) severe toxic heart disease, such as ventricular fibrillation or flutter, III degree atrioventricular block, cardiogenic shock or congestive heart failure, sudden cardiac death.

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