Eosinophilic pustular folliculitis

Introduction

Introduction to eosinophilic pustular folliculitis Eosinophilic pustular folliculitis is a shallow inflammation of the hair follicle. The pathogens are mostly Staphylococcus aureus, sometimes Staphylococcus aureus, often caused by insect bites, injuries, and scratches. There are pustules under the corners of the hair follicle opening. There are a large number of neutrophils, residual keratin and necrotic epithelial cells in the pustules. Epidermal cells edema around the pustule, connective tissue edema around the upper part of the hair follicle, vasodilatation, and more neutrophil infiltration around it. basic knowledge The proportion of illness: 0.06% Susceptible people: no special people Mode of infection: non-infectious Complications: Asthma Eczema

Cause

Causes of eosinophilic pustular folliculitis

Cause:

In the early stage, the hair root outer sheath cells, intercellular edema, eosinophils, neutrophils and monocytes infiltrated, and abscesses formed in the hair follicles. The abscess contained a large amount of the above cells.

Prevention

Eosinophilic pustular folliculitis prevention

1. In the units prone to pyoderma (such as some factories, agricultural machinery stations, primary schools, etc.), extensive publicity and education on the prevention and treatment of suppurative skin diseases, regular preventive inspections, as far as possible to eliminate all factors.

2. Pay attention to skin hygiene, strengthen physical exercise and increase skin resistance.

3. Maintain the integrity of skin function. For skin diseases, especially pruritic skin diseases, timely treatment should be carried out to prevent skin damage and avoid irritation such as scratching and skin friction.

4. Clothes, towels, basins, etc. are prohibited from public use to prevent contact with infection. The patient should be properly isolated. The dressings and contact materials used by the patient should be strictly disinfected or burned. During the illness, it is forbidden to use the liquid to clean the skin lesions. Wash the affected area with tap water to prevent extension.

5. When you are sick, you should ban alcohol or spicy food, and eat less food.

Complication

Eosinophilic pustular folliculitis complications Complications, asthma, eczema

Often accompanied by asthma and eczema.

Symptom

Eosinophilic pustular folliculitis symptoms Common symptoms Pustular eczema pustular acne papules itching red scaly scales

Male-dominated, male to female ratio is about 5:1, the age of onset is 16 to 61 years old, more common in 20 to 30 years old, rash occurs on the face, chest and back, upper extremity extension, is a follicular red papule, the top is often There are pustules, surrounded by 1 ~ 2mm blush, scattered at the beginning, gradually clustered later, can form red patches, a small amount of scales and pigmentation after the center of the papules subsided, new papules on the edges, and enlarged to the surrounding, skin lesions When it is expanded to a certain extent, it will no longer increase, the boundary is clear, and it can be repeated. The duration of the rash and the interval of recurrence are uncertain. The palmar rash is similar to palmoplantar pustulosis.

There is mild itching in the rash, and there is general malaise when it is aggravated.

Most patients have a history of acne or seborrheic dermatitis, or both. The family often has asthma and eczema.

Examine

Examination of eosinophilic pustular folliculitis

The white blood cells were moderately increased, and the eosinophils were significantly increased to 0.46×10 9 /L, which generally fluctuated between (0.02 and 0.26)×10 9 /L. No pathogenic bacteria were found in the bacterial culture.

Early in the hair root outer sheath cells, intercellular edema, eosinophils, neutrophils and monocytes infiltration, abscess formation in the hair follicles, abscess contains a lot of these cells, hair follicles and blood vessels around the eosinophils, The granulocytes and monocytes infiltrate and the hair is intact.

Diagnosis

Diagnosis and identification of eosinophilic pustular folliculitis

According to clinical manifestations, laboratory tests and pathological sections, the diagnosis of this disease is not difficult.

1. Impetigo: It is a highly contagious, bacterial skin infection that occurs in younger children, especially babies. The disease mainly affects the child's mouth and nose skin and the baby's diaper area, and sometimes it can appear in other parts of the body. Bacteria can enter the body through wounds, insect bites or certain skin diseases such as atopic eczema and hemorrhoids, causing impetigo.

2. Pustular psoriasis: less common, the cause is unknown, with general malaise, fatigue and joint swelling, yellow-white sterile small pustules appearing suddenly on the erythema, the needle to the size of the miliary, the initial small piece Later, it will be merged into a "pup lake", which can diffusely distribute the whole body within a few weeks.

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