tropical sprue
Introduction
Introduction to tropical inflammatory diarrhea Tropical inflammatory diarrhea (tropicsprue) occurs in tropical residents and is most common in Southeast Asian countries such as South America, Africa, and India. It can be criticized at any age. In recent years, the disease occurring in the tropics has been classified as "infectious malabsorption", and the disease is divided into parasitic (ie, giardiasis) and non-parasitic (tropical inflammatory diarrhea). Kind. basic knowledge Sickness ratio: 0.05%-0.07% Susceptible people: good for tropical residents Mode of infection: non-infectious Complications: anemia
Cause
Causes of tropical inflammatory diarrhea
It is believed that chronic intestinal infections, which may be caused by one or more pathogenic microorganisms or parasites, are not clearly related to the diet of the wheat gelatin. The disease is epidemic, seasonal, and broad-spectrum antibiotics are effective, but feces, intestinal contents and No pathogenic bacteria were found in the intestinal mucosa, and nutrient deficiencies such as protein, vitamin B, and folic acid may be related to the onset of the disease, but it is not an important cause.
Intestinal mucosa villi deformed irregularly, coarse or flattened; tongue-shaped, ridged or flat, curly, jejunal mucosa biopsy has a long glandular fossa, nuclei cell nuclear hypertrophy, argyrophilia, epithelial cells are square or Flat shape, goblet cells decreased, epithelial cell enzyme activity decreased, electron microscopic examination showed irregular microvilli, agglomeration of the group, microsomes and mitochondria increased, some of them also had superficial or atrophic gastritis.
Prevention
Tropical mouth inflammatory diarrhea prevention
Reasonable diet, food intake should be more nutritious, appropriate fluid replacement, correct electrolyte imbalance.
Complication
Tropical inflammatory diarrhea complications Complications anemia
Frequent anemia, hypoalbuminemia, abnormal glucose tolerance and other complications.
Symptom
Symptoms of tropical inflammatory diarrhea Common symptoms Stomatitis, diarrhea, weakness, weakness, cleft palate, steatorrhea
There are fatigue, abdominal pain, diarrhea, stool 1 or 2 times a day, or more than 10 times, the amount of feces is large, it is mushy, pale and stinky, greasy foamy, about 30% of cases have steatorrhea, hypoalbuminemia The oral protein tolerance test showed that the absorption was delayed, 50% of the patients had abnormal glucose tolerance, about 90% of the cases had reduced urine output from the xylose absorption test, and the vitamin A and B12 absorption tests were also abnormal.
Examine
Examination of tropical inflammatory diarrhea
Small intestinal biopsy, vitamin A and B12 absorption test, xylose absorption test, glucose tolerance test, oral protein tolerance test.
Diagnosis
Diagnosis and diagnosis of tropical inflammatory diarrhea
Diagnosis can be made according to the area of the disease, clinical manifestations, impairment of intestinal absorption function and pathological manifestations of small intestine.
It should be differentiated from intestinal giardiasis, intestinal amebiasis, inflammatory bowel disease, glucan enteropathy and vitamin B12 deficiency.
