Skin diseases caused by arsenic and its compounds
Introduction
Introduction to skin diseases caused by arsenic and its compounds 1. Industrial application: smelting and roasting arsenic-containing ore, sublimed to obtain arsenic trioxide (As2O3), used in the glass industry and insecticidal, rust-removing, anti-corrosion. Arsenic trichloride is used in the radio industry and porcelain polishes to produce arsenic-containing pigments such as copper arsenate (Paris Green). Arsenic-containing pesticides such as calcium arsenate [Ca3(AsO4)2], sodium arsenite (NaAsO2) and arsenic pentoxide (As2O5). It can also be used to produce arsenic drugs, such as 914 injections. 2. Physical and chemical properties: arsenic has three kinds of allotropes of ash, yellow and black, insoluble in water, soluble in nitric acid and aqua regia. It is easily oxidized in humid air, and the toxicity of elemental arsenic is extremely low; arsenic compounds such as oxides, salts and organic compounds are toxic, and the toxicity of trivalent arsenic compounds is stronger than that of pentavalent arsenic compounds. Skin diseases caused by arsenic and its compounds are dermatitis and skin lesions caused by skin exposure to arsenic dust. basic knowledge The proportion of illness: 0.003% Susceptible people: no special people Mode of infection: non-infectious Complications: lung cancer
Cause
Causes of skin diseases caused by arsenic and its compounds
Causes:
Skin contact with arsenic causes dermatitis, long-term exposure to arsenic dust, can cause excessive keratinization of the skin.
Pathogenesis:
Skin contact with arsenic dust can cause dermatitis, long-term exposure to arsenic dust, can cause hyperkeratosis of the skin, long-term inhalation of arsenic dust or gas, can cause dryness of the nasopharynx, rhinitis, nosebleeds, skin hypersensitivity and muscle tenderness On the basis of keratosis of arsenic, a part of cancer can occur in situ, or visceral tumors, especially lung cancer.
Prevention
Prevention of skin diseases caused by arsenic and its compounds
Enhance personal protection, including wearing long rubber gloves and long boots. Use long aprons, wear protective glasses, masks, etc., to avoid contact with air contaminated by arsenic and its compounds. If contact is inadvertently, it should be cleaned immediately to avoid damage to the skin.
Complication
Skin disease complications caused by arsenic and its compounds Complications
Concurrent visceral tumors, especially lung cancer, occur more often after exposure to arsenic for many years.
Symptom
Symptoms of skin diseases caused by arsenic and its compounds Common symptoms Sensory allergic papules Hair loss Herpes nosebleeds
Skin contact with arsenic dust can cause dermatitis. Skin lesions often occur in wrinkles or wet areas, such as mouth, eyelids, armpits, scrotum, waist, groin and finger (toe), which are characterized by follicular papules, herpes, Acne-like rash, etc., the main feeling of pain or irritation, if not treated can form intractable ulcers.
Long-term exposure to arsenic dust can cause excessive keratinization of the skin, especially in the palm and sputum. It is characterized by multiple keratotic rashes with clear or diffused edges; it can also be caused by the face and neck and the parts susceptible to friction and wrinkles. Diffuse or into a grayish brown (black) pigmentation, or a small piece of pigment to reduce plaque, and some can be freckled-like performance, a small number can cause hair loss, nails can lose luster and smooth, thin and brittle, appear White stripes with a width of 1 to 2 mm (Mie's line).
Long-term inhalation of arsenic dust or gas can cause dryness of the nasopharynx, rhinitis, nosebleeds, and even a few nasal septum perforations; can cause conjunctivitis, laryngitis, bronchitis, etc., can also cause general neurasthenia syndrome.
Peripheral neuritis is characterized by skin hyperesthesia and muscle tenderness.
On the basis of arsenic keratosis, part of it can occur in situ cancer, or re-concurrent visceral tumors, especially lung cancer, which occurs many years after exposure to arsenic.
Examine
Examination of skin diseases caused by arsenic and its compounds
Chest pain, difficulty breathing. Gas inhalation of cesium trichloride in water can cause pulmonary edema.
Diagnosis
Diagnosis and diagnosis of skin diseases caused by arsenic and its compounds
After exposure to arsenic, the arsenic content of blood, nails and hair increased, and its significance remains to be studied. Urinary arsenic determination contributes to the diagnosis of arsenic poisoning.
Arsenic, arsenic ore, arsenic compound skin contact history, inhalation of arsenic dust or gas, long-term use of arsenic compounds, etc., occur in wrinkles or wet areas, such as mouth, eyelids, armpits, scrotum, waist, groin and fingers (toe) ), manifested as follicular papules, herpes, acne-like rash, etc., the main pain or irritation can be diagnosed.
