PUVA freckles

Introduction

Introduction to PUVA Freckle It is medically known as sputum cells or melanocyte sputum, which is a skin manifestation caused by an increase in melanocytes in the epidermis and dermis. If it is higher than the leather, dome or nipple-like appearance or pedunculated rash, it is clinically called intradermal sputum; slightly higher than the leather surface is mixed , not higher than the leather surface is the junction . PUVA lenticulitis is a pigmented disease caused by PUVA treatment or UVA irradiation, and its occurrence is related to a large accumulation of UVA. It is usually characterized by limited pigmentation spots, diffuse freckles, large irregular spots or persistent gray-white spots. basic knowledge Sickness ratio: 0.0001% Susceptible people: no special people Mode of infection: non-infectious Complications: freckles

Cause

PUVA freckle-like cause

(1) Causes of the disease

A pigmentation disease caused by PUVA treatment or UVA irradiation is associated with a large accumulation of UVA.

(two) pathogenesis

The pathogenesis is still not clear, and it is related to the large accumulation of UVA.

Prevention

PUVA freckle-like prevention

The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. Therefore, it is impossible to directly prevent the disease against the cause. Early detection, early diagnosis, and early treatment are of great significance for indirect prevention of this disease. For the aging of the corpus callosum that affects the appearance, do not pick it up to avoid infection.

Complication

PUVA freckle-like complication Complications freckles

Generally no special complications.

Symptom

PUVA Freckle-like symptoms Symptoms Freckles pigmentation skin

Symptoms include skin blemishes, freckles, and pigmented spots. Often manifested as limited pigmentation spots, diffuse freckle-like sputum, large irregular spots or persistent gray-white spots.

Examine

PUVA freckle-like examination

Clinical skin examination: Atypical sputum may become malignant, such as very dark sputum, uneven pigmentation, uneven or irregular edges, unclear boundaries, left and right asymmetry, and statistically larger than 5 mm in diameter. Some patients may have ulceration, exudation, etc. on the surface of the corpus callosum.

Laboratory tests: blood routine, C-reactive protein, erythrocyte sedimentation rate, myocardial enzyme spectrum, liver function, renal function, etc.

Diagnosis

Diagnosis and identification of PUVA freckles

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

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