foot and mouth disease
Introduction
Introduction to Foot and Mouth Disease Foot and Mouth Disease (FootandMouthDisease), also known as aphthora fever, is a viral sexually transmitted disease that invades ungulates such as cattle, sheep and pigs. It is very harmful to livestock. The human body is usually obtained because the person directly comes into contact with the sick animal or when the milk is introduced into the human body through the tiny wound, and occasionally occurs through the infection of food such as milk and butter, and it is generally difficult for people to infect each other. basic knowledge The proportion of illness: 0.003%, mostly infected by animals Susceptible people: no specific population Mode of infection: contact spread Complications: tenosynovitis mastitis
Cause
Causes of foot and mouth disease
Coxsackie A virus infection (35%):
The disease is caused by Coxsackie A virus. Some people think that it is related to O virus and C virus. It is a small RNA virus. When humans directly contact with sick animals or through milking, the virus enters the human body through tiny wounds. The incidence, occasionally through the milk, butter and other food infections, people are generally not easy to spread each other.
RNA virus infection (15%):
RNA virus is also called an RNA virus. Plant viruses, with a few exceptions (such as Caulif-low mosaic virus), are almost all RNA viruses. The RNA virus coronavirus has a diameter of 80-160 nm. During the replication process of the enveloped single-stranded RNA virus RNA, the enzyme activity of the error repair mechanism is very low and low, almost no, so the mutation is rapid.
Other factors (20%):
The virus is mainly found in vesicular skin and lymph. Diseased cattle are the main source of infection. The diseased cows during the rehabilitation and incubation periods can also be detoxified. The disease is mainly caused by respiratory and digestive tract infections, and can also be infected through mucous membranes and skin. Its spread is both sprawling and leaping, and it can occur all year round.
Prevention
Foot and mouth disease prevention
1. Reduce the number of places where there are many people when the foot-and-mouth disease is popular.
2. Keep air flowing.
3. Wash your hands thoroughly after meals, after going to the toilet and after finishing your baby's diapers or other stolen goods.
4. Cover your nose when coughing or sneezing.
5. Children's toys or utensils should be cleaned if they are contaminated by flying shovel.
Complication
Foot and mouth disease complications Complications Tenosynovitis mastitis
Common complications are:
1. Form an ulcer.
2. Infection.
3. Serious people can cause death.
The complications of foot-and-mouth disease often occur in the pathogenesis of bacterial suppuration and necrosis in the affected part of the tissue, sometimes manifested as multi-layered suppurative dermatitis or partial exfoliation of horny shell, tenosynovitis, mastitis and gastroenteritis, etc. Cardiac, endocrine diseases (pancreas, adrenal gland, etc.) and infertility, these animals are generally eliminated due to low productivity.
Symptom
Foot and mouth disease symptoms common symptoms lymph node enlargement fever
The incubation period is 2 to 10 days. The patient begins to have fever, headache, general malaise, congestion of the oral mucosa, dryness and burning sensation. After 2 to 3 days, blisters appear on the oral mucosa, nasal mucosa, lips, palms and fingers. At this time, the body temperature drops to normal, the rash gradually enlarges or fuses into bullae, the blister is transparent or turbid, the blister breaks into a shallow ulcer, and the nearby lymph nodes are swollen. The condition of the infant is heavier than that of the adult, and the course of disease is one week.
Examine
Foot and mouth disease check
Histopathology: deep finite vesicular blister in the skin and mucous membranes, with nucleus inclusions in adjacent cells.
Diagnosis
Diagnosis and diagnosis of foot and mouth disease
According to the history of exposure to sick animals. Symptoms such as blisters, ulcers and fever can occur in the hands, feet and mouth, which can be diagnosed. Conditional blister virus isolation, can be confirmed by culturing a virus or serum to detect specific complement binding and neutralizing antibodies.
