Lobo blastomycosis
Introduction
Introduction to Lobo's bud disease Lobomycosis, also known as keloid-like germination, is a chronic skin granuloma caused by a Loboaloboi. basic knowledge The proportion of illness: 0.025% Susceptible people: no special people Mode of infection: non-infectious Complications: nodular erythema
Cause
The cause of lobo bud disease
Bacterial infection (45%):
There are many reports of infection of dolphins in the bacterium, suggesting that its life history includes saprophytic in watery environment. The artificial culture of this bacterium has yet to be improved and the animal vaccination yield is very small. Its pathogenicity is very low, and the infection may be related to trauma. .
Trauma factors (25%):
The infection may be related to trauma. The pathogen enters the skin along the wound, producing nodules at the invagination, higher than the leather surface, brown or purple, the surface is smooth and elastic, and there is no blush around. The damage is often concentrated in one place. Through self-spreading or self-inoculation, the damage gradually increases, the symptoms are mild, itching is not painful, similar to benign tumors or keloids. In a few cases, due to trauma, there may be ulceration and exudation, surface scarring, and even lymphatic dissemination. Causes swelling of nearby lymph nodes, but no involvement of mucous membranes, internal organs and bones.
Prevention
Lobo bud disease prevention
Attention to prevent inflammatory cell infiltration, parakeratosis, acanthosis thickening without pseudo-epithelial neoplasia and intraepithelial abscess. GMS staining clearly shows that the strain is a chain composed of spheroid cells with a diameter of 7 to 14 m (average 9.5 m), and each cell is connected to a neighboring cell with a narrow neck to form a branch. Some yeast cells can be found in giant cells and macrophages, but most of them surround these cells.
Complication
Lobo bud disease complications Complications nodular erythema
The pathogen enters the skin along the wound, producing nodules at the invagination, higher than the leather surface, brown or purple, the surface is smooth and elastic. There is no redness around the damage. It is often concentrated in one place. With further propagation through self-spreading or self-inoculation, the damage gradually increases. Large, conscious symptoms are slightly itchy and painless, similar to benign tumors or keloids in a few cases due to trauma, there may be ulceration and exudation, surface scarring. Even spread through the lymph, leading to swollen lymph nodes nearby.
Symptom
Lobo sclerotium symptoms common symptoms crusted nodules lymphadenopathy
The disease may begin to have skin trauma, the pathogen enters the skin along the wound, produces nodules at the invagination, is higher than the leather surface, brown or purple, the surface is smooth and elastic, there is no redness around, and the damage is often concentrated in one place, with further Breeding, through self-spreading or self-inoculation, the damage gradually increases, the symptoms are mild, itching is not painful, similar to benign tumors or keloids. In a few cases, due to trauma, there may be ulceration and exudation, surface scarring, and good to the calf. The torso and waist, other parts such as the ear wheel, arm, neck and buttocks have also been reported, even spread through the lymph, leading to the swelling of the nearby lymph nodes, but the mucosa, internal organs and bones are not involved.
Examine
Lobo bud disease inspection
Direct microscopic examination of pathogens: double-walled round, arranged in chain spores, short bridges between spores.
Histopathology: nodular lesions are located between the epidermis and subcutaneous tissue, showing a granuloma-like appearance. The fibrous tissue is separated by a large number of giant cells and tissue cells. The diameter of giant cells can reach 40-80 m. In the older lesions, there may be inflammatory cells. Infiltration, keratosis, acanthosis thickening, no pseudoepithelial neoplasia and intraepithelial abscess, GMS staining can clearly show that the strain is a chain of 7 ~ 14m (average 9.5m) spheroid cells, each cell It is connected to adjacent cells by a narrow neck and can form branches. Some yeast cells can be found in giant cells and macrophages, but most of them surround these cells.
Diagnosis
Diagnosis and identification of lobo blame
diagnosis
Diagnosis was made according to clinical manifestations, pathological examination and direct microscopic examination.
Differential diagnosis
Mainly differentiated from skin diseases with similar clinical manifestations, such as sputum, tumor, leprosy (Hansen disease), allergic cutaneous leishmaniasis, pigmented blastomycosis and paracoccal disease.
