ovarian fibromatosis
Introduction
Introduction to ovarian fibromatosis Ovarian fibromatosis is a relatively rare condition that occurs in young women, and Young (1984) first called it ovarian fibromatosis. Because it is associated with severe ovarian edema in the age distribution of patients, the clinical manifestations are the same, and the pathological features are similar, which may reflect different expression patterns of the same disease. In the past literature, the two are often confused, and they are regarded as true. Tumorous. The prognosis of this disease is good. basic knowledge The proportion of illness: 0.003% Susceptible people: women Mode of infection: non-infectious Complications: pulmonary hypertension
Cause
Causes of ovarian fibromatosis
(1) Causes of the disease
The cause of ovarian fibromatosis is still unknown.
(two) pathogenesis
1. The morphology of the naked eye is about 6/7 unilateral, the ovary may be partially or completely involved, the affected ovary is enlarged, the diameter is 6-12 cm, the average is 8 cm, the appearance is white, smooth or nodular, lobulated, and the solidity of the cut surface Hard, mostly white, a few gray or yellow, about 1/3 visible small capsule, the maximum diameter of the capsule can reach 2.5cm.
2. The tissue-shaped lesions of the fusiform fibroblasts proliferate and produce collagen fibers of varying degrees, surrounding the normal ovarian structure, including the follicles and corpus luteum at various stages, and the small sac seen by the naked eye is the saclike follicle remaining in the lesion, the luteinization room. The cytoplasmic cells are occasionally found in proliferating fibroblasts or normal ovarian stroma. In a few cases, granule cell nests or hollow small tubular structures like support cells appear in fibroproliferative foci, and half of the cases have focal interstitial edema.
Prevention
Ovarian fibromatosis prevention
It is very important to maintain a good attitude, to maintain a good mood, to have an optimistic, open-minded spirit, and to be confident in the fight against disease. Don't be afraid, only in this way can you mobilize your subjective initiative and improve your body's immune function.
Complication
Ovarian fibromatosis complications Complications pulmonary hypertension
Some scholars have reported a case of death due to right pulmonary embolism caused by intra-abdominal disseminated fibromatosis, bilateral peripheral pulmonary embolism and right lower lobe segmental infarction.
Symptom
Ovarian fibromatosis symptoms Common symptoms Menstrual volume, vaginal irregular bleeding, abdominal pain, amenorrhea, uterine attachment, masculinization
About half of the patients with ovarian fibromatosis are infertile, and the rest are only 1 or 2 pregnancies. More than half of menstrual abnormalities include irregular vaginal bleeding, menorrhagia or amenorrhea, a few with masculinization and multiple hairy, such as tumor pedicle torsion Abdominal pain, gynecological examination can be associated with unilateral or bilateral attachment lumps.
Examine
Examination of ovarian fibromatosis
1, physical signs: tumors are mostly unilateral, bilateral accounted for 4% to 10%. Round, kidney or lobulated nodules. The surface is smooth, the envelope is intact, solid, and the texture is hard. The cut surface is solid, the braided structure is obvious, gray or white, and occasionally hemorrhage or cystic change.
2, under the microscope examination: tumor cells long fusiform, less cytoplasm, no lipid drops. The cells are closely packed and woven or matted. Collagen fiber is rich and can be accompanied by a wide range of glass-like changes. Tumor cells have no typical shape and no mitotic figures.
3, other examinations: B-ultrasound, CT, laparoscopy.
Diagnosis
Diagnosis and diagnosis of ovarian fibromatosis
According to the clinical manifestations and symptoms, laboratory tests, auxiliary tests can make a diagnosis.
1. Ovarian edema The cortical layer and medulla are highly edematous, cystic, edema tissue is scattered in the follicles, and there is edema fluid overflowing in the section, but there is no fibrous cell and collagen fiber surrounding the structure of the follicle.
2. Ovarian fibroids The disease occurs mostly in elderly women. The fibers of the facet hyperplasia are arranged in a woven pattern. There is no normal ovarian structure and usually no endocrine activity.
