green monkey disease
Introduction
Introduction to Green Monkey Disease Green monkey disease (greenmonkeydisease) is also known as African hemorrhagic fever (Africahemorrhagicfever), Marburg-Ebera (Marburg) virus disease. basic knowledge The proportion of illness: 0.0005% Susceptible people: no special people Mode of infection: body fluid transmission, respiratory tract transmission Complications: disseminated intravascular coagulation
Cause
Cause of green monkey disease
(1) Causes of the disease
Caused by the Marburg virus, a cylindrical baculovirus that was infected by humans in close contact with monkeys, first in Europe, and contacted with laboratory workers from African green monkeys in Uganda, hence the name, the disease is An acute skin allergic bleeding disorder.
(two) pathogenesis
The Marburg-Marburg virus is transmitted to humans. This disease is an acute skin sensitizing bleeding disorder, and the pathogenesis is still unclear.
Prevention
Green monkey disease prevention
1. Ask the passengers from the infected area for physical health. Patients with symptoms of high fever, nausea, vomiting, diarrhea, headache, muscle pain should be restricted from entering the country. It is forbidden to import monkeys from infected areas, and other animals should also be quarantined.
2. Once the case is found, it should be reported immediately, closely separated, and close contacts should be observed and isolated. Investigate contacts and sources of infection to identify and closely monitor all of them who are in close contact with the patient within 3 weeks of the onset of illness.
3. The medical staff should take respiratory protection when contacting the patient, the patient's excrement, sputum, blood and all items that the patient has contacted, autoclaved, incinerated or boiled. Laboratory research is highly dangerous, and laboratories conducting relevant experiments should meet P4 standards. When raising and dissecting suspicious monkeys, strict precautions should also be taken.
Complication
Green monkey disease complications Complications, disseminated intravascular coagulation
Some patients can develop DIC.
Symptom
Symptoms of green monkey disease common symptoms convulsions diarrhea lymph nodes swollen maculopapular coma nausea and vomiting renal failure myalgia
The incubation period is 3 to 9 days. Sudden onset, fever, discomfort, severe headache, conjunctivitis, vomiting, diarrhea, myalgia and other systemic symptoms, systemic lymphadenopathy, severe liver, heart, pancreas, kidney, hematopoietic organs and Central nervous system, acute fever often lasts for 2 weeks, about 1/3 of patients often on the 8th to 17th day, due to myocarditis, renal failure, convulsions, coma and death, onset 5 to 7 days, in the buttocks, trunk, limbs There is scattered follicular red papules. After 1 day, the maculopapular rash is merged, and hemorrhagic diffuse erythema is severe. The rash often resolves after 2 weeks, desquamation, palmar palsy, heavier desquamation at the extremities, and small red on the buccal mucosa. Point, blisters appear in the soft palate, the tonsils are swollen, and some patients may develop DIC.
Examine
Green monkey disease check
Peripheral blood leukocytes and thrombocytopenia, prolonged thrombin time, elevated serum ALT, GPT and amylase, can be isolated in the pharynx, blood, urine.
Diagnosis
Diagnosis and diagnosis of green monkey disease
Can be diagnosed based on epidemiology and clinical manifestations.
