Fusarium disease
Introduction
Introduction to Fusarium Fusarium disease, also known as Fusarium, is a skin, corneal or systemic infection caused by Fusarium. It belongs to the genus Chrysosporium. Fusarium is a fungus widely distributed in nature. It is mostly saprophytic. It is easy to invade the grain in the field and the various foods stored in the warehouse. basic knowledge The proportion of illness: 0.001% - 0.004% Susceptible people: no special people Mode of infection: non-infectious Complications: sepsis and bacteremia
Cause
Cause of Fusarium disease
(1) Causes of the disease
Skin, cornea or systemic infection caused by Fusarium.
(two) pathogenesis
Fusarium is a conditional pathogen, and skin damage and human immunity are prone to disease. Common pathogens include F. moniliforme, F. solani, and Fusarium oxysporum. ), Fusarium is one of the most common pathogens causing keratitis and corneal ulcers. It can also cause endophthalmitis, osteomyelitis, arthritis, sinus infection, onychomycosis and foot sore, and Fusarium on burned skin. It can multiply on cockroaches and tissue debris, but generally does not invade surrounding tissues, and can even cause disseminated infection.
Prevention
Fusarium disease prevention
Fusarium is a conditional pathogen. Skin damage and decreased immunity can cause illness. Common pathogens include F. moniliforme, F. solani, and F. oxysporum. Fusarium is one of the most common pathogens causing keratitis and corneal ulcers. It can also cause endophthalmitis, osteomyelitis, arthritis, sinus infection, onychomycosis and foot swelling. Pay attention to prevention from the above aspects.
Complication
Fusarium disease complications Complications sepsis and bacteremia
Fusarium oxysporum can produce a metabolite, T-2 toxin, which can lead to necrosis of bone marrow hematopoietic tissue and bleeding of internal organs.
Symptom
Fusarium disease symptoms common symptoms fatigue nausea and vomiting diarrhea dizziness corneal ulcer neutropenia
The main symptoms of human and livestock poisoning caused by fusarium are obvious weakness, headache, dizziness, vomiting, diarrhea and severe disorders of the central nervous system, and another food toxic leukopenia, mainly caused by the sclerotomy After the bacteria and Fusarium oxysporum invade the grain and cause strong toxins in the field overwintering, Fusarium oxysporum can produce a metabolite, T-2 toxin, which can cause necrosis of bone marrow hematopoietic tissue and bleeding of internal organs. Fusarium can also cause systemic diseases, invading the urethra, bladder, brain, kidney, lung, heart, bone, pancreas, etc., disseminated infections are more common in neutropenia and bone marrow transplants.
Examine
Examination of Fusarium disease
1. Direct microscopic examination: Take dandruff, pus, nails, corneal ulcer scrapings, living tissue and cadaver tissue specimens, microscopically visible branches, separated hyphae, similar to the microscopic features of Aspergillus.
2. Fungal culture: On the sandcasting medium, the aerial hyphae are abundant, and the large and small conidia are visible under the microscope.
Histopathological examination: with direct microscopic examination, the branches and separated hyphae can be seen.
Diagnosis
Diagnosis and identification of Fusarium disease
diagnosis
According to clinical manifestations, dandruff, pus, nails, corneal ulcer scrapings, living tissue and cadaver tissue specimens, microscopically visible branches, separated hyphae, microscopic features similar to Aspergillus, cultured in Sandcastle On the base, the aerial hyphae are abundant, and the large and small conidia are visible under the microscope, and the diagnosis is not difficult.
Differential diagnosis
The identification of Aspergillus and Penicillium depends only on culture, and the positive rate of blood culture of Fusarium is higher than that of Aspergillus.
