Colorado Tick Fever

Introduction

Introduction to Colorado Hot Colorado ticker (Coloradotickfever) is an acute viral disease caused by the Colorado virus that is transmitted by sputum. Clinical features of fever, headache, back pain, bimodal fever for 1 week, and leukopenia. basic knowledge The proportion of sickness: 0.00001% Susceptible people: no specific population Mode of infection: bite spread Complications: meningitis

Cause

Colorado fever

(1) Causes of the disease

The Colorado virus is a double-stranded RNA virus, 35 to 50 nm, and the outer envelope contains lipoprotein, so it is sensitive to ether.

(two) pathogenesis

The granuloma-like primary lesion can be seen in the biteed part. The main lesion of the rash is swelling of the endothelial cells of the capillaries and small arteries and venules, hyperplasia and metastasis, and vascular embolism has mononuclear and plasma cell infiltration around the vascular embolism. , produces a series of clinical symptoms.

Prevention

Colorado Heat Prevention

1. Prevention

(1) Eliminate the source of infection

Prevent hard bites. Especially when conducting outdoor activities in spring and summer in popular areas, it is more important to pay attention to personal protection.

(2) use of vaccine

Currently, two vaccines are available: both inactivated vaccines and live attenuated vaccines can be used. However, in practical applications, its significance is not particularly large.

2, matters needing attention

After the patient recovers, blood is not available for half a year.

Complication

Colorado fever complications Complications meningitis

The disease may be complicated by aseptic meningitis, encephalitis, and bleeding, but it is very rare.

Symptom

Colorado fever symptoms common symptoms rash rash rash conscious disorder eye pain high heat photophobia chills myalgia

What are the performances and how to diagnose in Colorado?

The incubation period is 3 to 7 days. The chills and high fever are 38 to 40 °C. Headache, eye pain, pain after eyelids and photophobia. Myalgia is most obvious on the back and legs. The body surface is 2 to 3 days after the examination. Pharyngeal flushing, lymph node swelling is not obvious, occasionally splenomegaly, 10% of patients can see rash, spotted or maculopapular rash, distributed throughout the body, sometimes visible in the extremities, 50% of cases are bimodal fever, in the second to third disease After the body temperature dropped to normal, the above symptoms subsided, but after 1 to 2 days, the body temperature rose again, the symptoms reappeared, and heavier than the initial stage. After the second fever lasted 2 to 4 days, the symptoms subsided, but the weakness was weak for 1 to 2 weeks. Can be improved, some cases have only one fever, and some cases have a fever for 5 to 8 days or have fever 3 times, a small number of patients may have aseptic meningitis or encephalitis, manifested as neck stiffness, disturbance of consciousness and bleeding, cerebrospinal fluid Change and so on.

Clinical diagnosis

3 to 7 days before the disease, patients with a history of travel in the epidemic area should consider this disease, especially those with secondary fever and leukopenia are more helpful in the diagnosis of this disease.

2. Laboratory diagnosis

Take the whole blood or serum of the patient to inoculate the suckling rat, and isolate the virus to confirm the diagnosis. Take the blood smear of the patient and directly stain by immunofluorescence. The virus can be diagnosed early in the red blood cells, and the double serum is used as the neutralizing antibody and the complement antibody. If the titer is increased by 4 times or more, the diagnosis can also be confirmed.

Examine

Colorado hot check

The white blood cell count decreased from the third disease day, and the decrease was more obvious after the second fever. It was 2.0×109/L, the neutrophil reduction was more significant, the lymphocytes were relatively increased, the thrombocytopenia, and the vacuolar abnormal lymphocytes were not. Rare, but the prognosis is good.

X-ray chest radiographs showed no abnormalities.

Diagnosis

Colorado Diagnostic Identification

Those with a history of tourism should be identified with the rumors of fever, Los Angeles spot fever, rabbit fever and leptospirosis, and clinical identification with influenza, typhoid fever, dengue fever, measles, etc.

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