Multiple pilosynomas in Cowden disease
Introduction
Introduction to multiple hairstem tumors in Cowden's disease Multipletrichilemmoma (also known as multiple hamartoma syndrome) is an autosomal hereditary skin disease with unique skin manifestations. The lesion is located on the face, mainly in the mouth and nose. Near the ear, it is a flesh-colored, pink or brown pimples, clinically similar to common warts. basic knowledge The proportion of illness: 0.0005% Susceptible people: no specific population Mode of infection: non-infectious Complications: breast cancer
Cause
The cause of multiple sporadic tumors in Cowden's disease
(1) Causes of the disease
The cause of the disease is not clear. It may be related to environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy.
(two) pathogenesis
The pathogenesis is still unclear. Histopathological examination was seen to be the same as single-shot chorionoma. Oral lesions can be manifested as fibromatous nodules, consisting of relatively acellular vortex-like fibers or fibrous vascular tissue with acanthosis.
Prevention
Multiple hairstem prevention in Cowden's disease
The etiology of multiple sporadic tumors in Cowden's disease is still unclear. Understanding the risk factors of tumors and formulating corresponding prevention strategies can reduce the risk of tumors. There are two basic clues to prevent tumors. Even if tumors have begun to form in the body, they can help the body to improve resistance. The current focus of cancer prevention and treatment work should focus on and improve those factors that are closely related to our lives, such as Quit smoking, eat properly, exercise regularly, and lose weight. Anyone who follows these simple and reasonable lifestyles can reduce their chances of developing cancer.
Complication
Multiple sclerosis complications in Cowden's disease Complications
Because the disease is accompanied by damage to the skin and mucous membranes, and there is a risk of concurrent tumors, clinical attention should be paid. For the destruction of skin integrity, it may cause skin bacterial infection or fungal infection due to patient scratching, usually secondary to low body constitution, or long-term use of immunosuppressive agents and fungal infections such as nail fungus, such as concurrent bacterial infection may have fever , skin swelling, ulceration and purulent secretion and other performance. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Symptoms of multiple hairstems in Cowden's disease Common symptoms Pap striatum keratoderma can be horny
Multiple hairstem tumors are found in all patients with Cowden's disease. The lesions are located on the face, mainly around the mouth, around the nose and ears. They are flesh-colored, pink or brown pimples, clinically similar to common warts, and in addition, dense mouths are visible. The papules, so that the lips, sputum and tongue are in the form of a special "big goose egg" stone, and there are multiple small acral keratosis. The incidence of breast cancer in women with this disease is high, and multiple hairsynthesis often precedes Breast cancer occurs, and other visceral malignancies are occasionally seen in Cowden's disease, but most are fibrous hamartomas, especially the breast, thyroid and gastrointestinal tract.
Examine
Examination of multiple hairsynthesis in Cowden's disease
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Histopathology: As with single-shot chorionoma, oral lesions can be manifested as fibromatous nodules, composed of relatively acellular vortex-like fibers or fibrous vascular tissue with acanthosis.
Diagnosis
Diagnosis and diagnosis of multiple hairstem tumor in Cowden's disease
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
The clinical manifestations of this disease are similar to those of common sputum. Therefore, the focus of this disease is differentiated from common sputum. Common sputum occurs in adolescents and is more common in fingers, back of hands, and feet. Skin and mucous membrane damage is the main cause of infection. The initial performance is a hard, small papule, grayish yellow or yellowish brown, and the surface is rough and keratinized. The disease develops slowly and can naturally subside. The HPV test is positive, and can be distinguished from multiple scleroma in the disease according to the pathological examination.
