endocrine proptosis

Introduction

Introduction to endocrine eyeballs Endocrine regulates the oxidation and metabolism of various organs and tissues of the human body, thus maintaining the normal health of the human body. If the secretion is too much or too little, it will cause diseases. Clinically, it can be divided into two types: thyroid toxic eyeball protrusion and thyrotropin-promoting eyeball protrusion. Endocrine ocular protrusions include thyroid-related, acromegaly-related and adrenal hyperfunction, but clinically mainly thyroid-related, also known as thyroid-related immune eyelid disease, is an important cause of eye protrusion in both adults and eyes. The disease refers to eyelid inflammation associated with thyroid dysfunction and immune system disorders, but clinical manifestations of hyperthyroidism, hypothyroidism or normal thyroid function, the latter also has the author's name for eye-shaped Graves disease. The disease is more common in adults, bilateral onset, the degree can be inconsistent. Some patients have a tendency to heal themselves. basic knowledge The proportion of illness: 0.001% Susceptible people: no special people Mode of infection: non-infectious Complications: exposed keratitis

Cause

Endocrine ocular protrusion

Thyroid toxic eyeball

The occurrence of thyroid toxic exophthalmos may be due to the sympathetic nerve being in an excited state, which causes the orbital smooth muscle to contract and pull the eyeball forward; on the other hand, the extraocular rectus muscle becomes thick and loose, thereby reducing the back of the eyeball. The pulling force plays a role in the movement of Ken's ball forward, and because the secondary fat in the sputum fills the gap left behind the eyeball, the eyeball cannot return to its original position even under external pressure.

Thyrotropin-promoting eyeball

The anterior pituitary hyperfunction or thyroid gland removal, caused by excessive secretion of thyrotropin, called pituitary exophthalmos (malignant exophthalmos), recent research results suggest that may be related to immune factors, under normal circumstances, thyroxine and promote The anti-meal effect between thyroxine is in equilibrium. Therefore, when the exophthalmia is in the process of performing a thyroidectomy, there is a risk of promoting the development of the eye.

Prevention

Endocrine eyeball prevention

Pay more attention to diet and no other effective preventive measures.

Complication

Endocrine ocular ocular complications Complications exposed keratitis

It can cause cleft palate and closed keratitis, and even purulent corneal ulcer or perforation. Retinal hemorrhage and papilledema can be found in the fundus.

Symptom

Endocrine ocular protrusion symptoms Common symptoms Corneal ulcers papilledema thyroid enlargement keratitis high intraocular pressure double vision

Thyroid toxic eyeballs:

Thyroid toxic exophthalmos, also known as exophthlmic goiter.

Graves disease is a combination of eyeballs and thyroid enlargement. It is divided into two types according to its thyroid function:

1, ocular Graves disease: eyeballs prominent, accompanied by diffuse thyroid enlargement, but normal thyroid function.

2, Graves eye disease: thyroid diffuse enlargement, eyeballs prominent, and the thyroid can be hyperthyroidism or low, each divided into two types:

One type is Graves disease, which is more common in clinic and more middle-aged women. It is an autoimmune disease, an activity of tissue metabolism and nervous system responsiveness, which may be triggered by the stress response of trauma.

The other type is thyrotropin-promoting eyeballs, mostly bilateral, middle-aged men are mostly, eye symptoms are more obvious than systemic poisoning symptoms, and progressive eye marks are also known as exophthalmia. The direction is straight forward, the early upper eyelids often retreat, the eyelids and conjunctiva are highly edematous, the contents of the eyelids are hard, which can cause cleft palate and closed keratitis, and even purulent corneal ulcers or perforation. Often accompanied by extraocular muscle paralysis, limited eye movement and double vision, retinal hemorrhage and papilledema can be found in the fundus, which is caused by obstruction of the retinal vein due to increased pressure in the eyelid. High intraocular pressure can still oppress the optic nerve. It causes cardiovascular limitation, reduces vision and glaucoma-type visual field defects, and can even cause optic atrophy.

Examine

Endocrine eyeball examination

Eye examination, if necessary, according to ultrasound examination and CT, MRI imaging examination.

Diagnosis

Endocrine eyeball diagnosis and differentiation

False eyeball protrusion: When the eyelid volume is small, the eyeball size is normal, or the eyeball volume is increased, such as bull's eye, water eye or high myopia, it may be a pseudo-eyeball.

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